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Patient Follow Up Articles & Analysis

41 news found

Galapagos and CellPoint presented encouraging initial data at ASH 2022 for GLPG5101, a CD19 CAR-T candidate manufactured at point-of-care

Galapagos and CellPoint presented encouraging initial data at ASH 2022 for GLPG5101, a CD19 CAR-T candidate manufactured at point-of-care

The dose levels that are evaluated in the Phase 1 part of the study are 50x106 (DL1), 110x106 (DL2) and 250x106 (DL3). As of 8 November 2022, 9 patients were enrolled; baseline and safety data for 8 patients were available (n=4 at DL1; n=4 at DL2). 7 patients reached the follow-up period of 28-days and were ...

ByGalapagos NV


IN8bio Reports Third Quarter 2022 Financial Results and Highlights Recent Company Progress

IN8bio Reports Third Quarter 2022 Financial Results and Highlights Recent Company Progress

INB-100 continued to demonstrate durable morphologic complete responses in the Phase 1 clinical trial in patients with leukemia; on track to announce additional data at upcoming ASH annual meeting. ...

ByIN8Bio Inc.


IN8bio to Present Positive Early Data from Ongoing Phase 1 Study of INB-100 at the 64th American Society of Hematology Annual Meeting

IN8bio to Present Positive Early Data from Ongoing Phase 1 Study of INB-100 at the 64th American Society of Hematology Annual Meeting

Data support the potential of INB-100 to induce long-term durable responses in patients with high-risk or relapsed acute myeloid leukemia (AML). Clinical activity observed includes continuing robust durability of relapse-free survival; all three patients in Cohort 1 remain alive and progression-free; ongoing durations of response exceed 12 months and extend ...

ByIN8Bio Inc.


Beyond Air Announces Positive Data for Inhaled Nitric Oxide (NO) to Treat COVID-19 with LungFit® PRO in a Poster Presentation at IDWeek 2022

Beyond Air Announces Positive Data for Inhaled Nitric Oxide (NO) to Treat COVID-19 with LungFit® PRO in a Poster Presentation at IDWeek 2022

“The analysis of the LungFit PRO study in VCAP patients further demonstrates improved efficacy on multiple parameters in the iNO treatment group compared to standard supportive treatment (SST). ...

ByBeyond Air Inc


ISET technology applied to DLA products from NSCLC patients identified more CTC than other systems

ISET technology applied to DLA products from NSCLC patients identified more CTC than other systems

“With the ISET technology, we were able to effectively extract CTC in higher numbers and from larger DLA volumes, in all cases thus increasing sensitivity for further studies of CTC in NSCLC patients,” said Dr. Menno Tamminga. Davide Brechot, Deputy Director and CTO of Rarecells Diagnostics commented: “Dr. ...

ByRarecells Diagnostics SAS


IN8bio Observes Durable Morphologic Complete Responses in Ongoing Phase 1 Clinical Trial of INB-100, an Allogeneic Gamma-Delta T Cell Therapy in High-Risk Leukemia Patients

IN8bio Observes Durable Morphologic Complete Responses in Ongoing Phase 1 Clinical Trial of INB-100, an Allogeneic Gamma-Delta T Cell Therapy in High-Risk Leukemia Patients

Patients remain in morphological complete remission (CR) with two patients over two years and a third over one year post-transplant, respectively. ...

ByIN8Bio Inc.


GI Dynamics Announces the Presentation of Updated Data Sets at the 2022 Meeting of the American Diabetes Association

GI Dynamics Announces the Presentation of Updated Data Sets at the 2022 Meeting of the American Diabetes Association

As of December 2021, data has been entered on 1001 patients with an increase of 130 patient records since 2019. The Worldwide EndoBarrier Registry continues to support a positive benefit:risk profile for patients with type 2 diabetes and/or obesity treated with EndoBarrier. ...

ByGI Dynamics, Inc.


AlloVir Reports Blinded, Preliminary, Phase 2 Data Supporting the Ongoing Study of Posoleucel, a Multi-Virus-Specific T Cell Therapy, for the Treatment of BK Viremia in Kidney Transplant Recipients

AlloVir Reports Blinded, Preliminary, Phase 2 Data Supporting the Ongoing Study of Posoleucel, a Multi-Virus-Specific T Cell Therapy, for the Treatment of BK Viremia in Kidney Transplant Recipients

Following this dosing period, patients are followed up through Week 24. ...

ByKalaris


Mersana Therapeutics Announces FDA Grant of Orphan Drug Designation to XMT-2056 for the Treatment of Gastric Cancer

Mersana Therapeutics Announces FDA Grant of Orphan Drug Designation to XMT-2056 for the Treatment of Gastric Cancer

This designation qualifies Mersana for potential incentives, including tax credits for certain trials, exemption from user fees and the potential for seven years of market exclusivity following approval (if granted). “The FDA’s decision to grant orphan drug designation to XMT-2056 for the treatment of gastric cancer is an important recognition of its potential in ...

ByMersana Therapeutics


Acutus Medical completes enrollment in IDE trial with its AcQBlate FORCE Sensing Ablation System

Acutus Medical completes enrollment in IDE trial with its AcQBlate FORCE Sensing Ablation System

Acutus Medical (Nasdaq: AFIB), an arrhythmia management company focused on improving the way cardiac arrhythmias are diagnosed and treated, today announced successful completion of patient enrollment in the company’s AcQForce™ Flutter Investigational Device Exemption (IDE) clinical trial which enrolled 110 patients at 21 sites globally. ...

ByAcutus Medical, Inc.


AlloVir Reports First Quarter 2022 Financial Results

AlloVir Reports First Quarter 2022 Financial Results

” Recent Highlights At the Annual Meeting of the European Society for Blood and Bone Marrow Transplantation (EBMT) in March 2022, AlloVir reported updated preliminary data from the open-label Phase 2 study assessing the safety and efficacy of posoleucel for multi-virus prevention in high-risk allo-HCT patients. The updated data set, which includes more ...

ByKalaris


Sequana Medical announces the completion of alfapump implantations in POSEIDON, the North American pivotal alfapump study

Sequana Medical announces the completion of alfapump implantations in POSEIDON, the North American pivotal alfapump study

Of the 71 patients enrolled in the Pivotal Cohort, 40 patients have been implanted with the alfapump. ...

BySequana Medical NV


Urgent Care For Children Collaborates With Visby Medical To Provide New Gold Standard Diagnostic For Sexually Transmitted Infections

Urgent Care For Children Collaborates With Visby Medical To Provide New Gold Standard Diagnostic For Sexually Transmitted Infections

Visby Medical, Inc. an innovative diagnostic company, today announced its agreement with Urgent Care for Children (UC4C) to offer the company’s new Sexual Health Click Test to patients for the detection of sexually transmitted infections (STIs) in female patients 14 years of age and older. ...

ByVisby Medical, Inc.


AlloVir Initiates Global Phase 3 Registrational Study of Posoleucel for Prevention of Life-Threatening Viral Infections from Six Common Viruses in High-Risk, Allogeneic Hematopoietic Cell Transplant Patients

AlloVir Initiates Global Phase 3 Registrational Study of Posoleucel for Prevention of Life-Threatening Viral Infections from Six Common Viruses in High-Risk, Allogeneic Hematopoietic Cell Transplant Patients

Safety and efficacy will continue to be followed through Week 26. Posoleucel has the potential to fundamentally transform the treatment landscape for allo-HCT by preventing life-threatening viral diseases and infections, either as a prophylactic therapy in high-risk patients or as a preemptive therapy in patients who have already reactivated one ...

ByKalaris


Study Finds Excellent Outcomes for Intermediate Risk Prostate Cancer Patients Treated with Isoray’s Cesium-131

Study Finds Excellent Outcomes for Intermediate Risk Prostate Cancer Patients Treated with Isoray’s Cesium-131

The study analyzed the outcomes for 335 intermediate-risk prostate cancer patients treated with Cesium-131 brachytherapy. Study patients had significant follow-up time. The median follow-up was 5.8 years, with a range of 4 to 8.9 years. The study found both the “favorable” (147 ...

ByTheragenics


DiscGenics Announces Presentation of Positive Interim Clinical Data from Phase 1/2 Study of Cell Therapy for Degenerative Disc Disease

DiscGenics Announces Presentation of Positive Interim Clinical Data from Phase 1/2 Study of Cell Therapy for Degenerative Disc Disease

Allogeneic discogenic cell therapy was well tolerated and produced clinically meaningful, statistically significant improvements in low back pain, function, and quality of life by 12 weeks following intradiscal injection; improvements were sustained at the one-year interim readout with additional data to follow at 18 and 24 months. ...

ByDiscGenics, Inc.


UroGen Announces Data that Shows In-Office Nephrostomy Tube Administration of Jelmyto® is Efficient for Doctors and Well Tolerated by Patients

UroGen Announces Data that Shows In-Office Nephrostomy Tube Administration of Jelmyto® is Efficient for Doctors and Well Tolerated by Patients

All patients underwent follow-up ureteroscopy with complete response in four patients. ...

ByUroGen Pharma, Inc.


New Data Show Statistically Significant Reduction in Chronic Cancer-Related Lymphedema with Early Detection Using ImpediMed’s L-Dex® Technology and Intervention

New Data Show Statistically Significant Reduction in Chronic Cancer-Related Lymphedema with Early Detection Using ImpediMed’s L-Dex® Technology and Intervention

Monitoring L-Dex scores allows clinicians across multiple specialties to provide individualized, proactive care that can help improve patient outcomes. The paper concludes the following: These statistically significant results demonstrate that [L-Dex] screening should be a standard approach for prospective breast cancer-related lymphedema (BCRL) surveillance. ...

ByImpediMed Inc.


Publication in The New England Journal of Medicine Confirms that Tens of Thousands of Women with Node-positive, Early-stage Breast Cancer Can Avoid Chemotherapy with the Oncotype DX Test

Publication in The New England Journal of Medicine Confirms that Tens of Thousands of Women with Node-positive, Early-stage Breast Cancer Can Avoid Chemotherapy with the Oncotype DX Test

In the study, postmenopausal women with 1 to 3 positive nodes and Recurrence Score results of 0 to 25 showed no benefit from chemotherapy after a median of five years of follow-up, meaning they can potentially avoid negative side effects of the treatment. ...

ByExact Sciences UK, Ltd.


Bluewind Medical Ltd. Completes OASIS Study Patient Enrollment

Bluewind Medical Ltd. Completes OASIS Study Patient Enrollment

Patients were screened and implanted at 23 centers in the United States, United Kingdom, The Netherlands, and Belgium. ...

ByBlueWind Medical

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