Protein Ubiquitination Articles & Analysis
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Attenuation of T cell receptor signaling by serine phosphorylation-mediated lysine 30 ubiquitination of SLP-76 protein. J Biol Chem. 2012;287(41):34091-34100. ...
The updated services provide scientists with comprehensive advanced platform for their projects. The ubiquitin proteasome system relies heavily on E3 ligases (UPS). As a major modulator of protein homeostasis, UPS is essential in signal transduction, mitophagy, DNA damage repair, inflammatory pathways, endocytosis, and cell cycle progression. ...
Ubiquitin modification induces protein degradation, which affects the function, localization, and activity of proteins. ...
The company has recently announced Protein Drug Modification Analysis service to help researchers determine the modification type, modification site, and modification structure of protein drugs. ...
Ubiquigent is a world-leading provider of biology assay services, novel chemistry and expertise in the emerging space of ubiquitin-system and protein degradation drug discovery. Historically, one of the main rate-limiting factors has been the availability of small molecules to support early drug development. ...