Skeletal Muscle Articles & Analysis: Older
13 news found
IVS’s Functional 3D tissue models recapitulate the physiological properties of human cardiac, smooth and skeletal muscle and connective tissue. Application of induced pluripotent technology allows to fabricate tissues in diseased states, e.g., hereditary cardiac diseases, cardiac fibrosis, cancer and orphan diseases. ...
IVS’s functional 3D tissue models reconstitute the physiological properties of human cardiac, smooth and skeletal muscle as well as connective tissues that support cancer growth. ...
The second, REVeRT (REconstitution Via mRNA Trans-splicing) technology platform, allows efficient reconstitution of large genes (>5Kb) in various tissues such as retina, brain, heart, liver, and skeletal muscle. The third, AAV Transactivation is a CRISPR-Cas–based AAV gene therapy platform that enables to regulate one or multiple genes in vivo. ...
The results, which will be presented today during the “Disease models and Clinical Applications: Musculo-skeletal Diseases” poster session at the American Society of Gene and Cell Therapy (ASGCT) annual meeting in Washington, D.C., demonstrate that a gene therapy using hematopoietic stem cells (HSC) significantly reduced toxic accumulation of glycogen in a mouse model ...
The published results showed statistically significant and clinically relevant evidence of CAP-1002’s ability to improve both skeletal and cardiac muscle function in patients in the latter stages of the disease. ...
Specifically, the study demonstrated that young men in the advanced stages of DMD experienced improvements in both skeletal and cardiac muscle function after receiving four doses of CAP-1002 over the course of one year. ...
” More specifically, the testing range of T,C&A Lab encompasses the following: l Repair materials for the skeletal-muscle system such as bones, teeth, joints, and tendons l Soft tissue materials such as skin, esophagus, respiratory tract, bladder and other l Cardiovascular system materials such as artificial heart valves, blood vessels, and ...
Clinically, this translates into the prevention of skeletal muscle contraction, phrenic nerve capture, and microbubbles which can be associated with traditional PFA, all while providing effective acute isolation. ...
At this HRS meeting, we reported early pre-clinical data suggesting that PFCA can be done without generating microbubbles or skeletal muscle contractions compared to more conventional PFA, even at much higher energy levels. ...
The fascia encompasses all the body’s internal structures, connecting everything together, even penetrating the muscles, organs and fatty tissues, and connecting bones to muscles and organs to each other. ...
Since their initial discovery more than 50 years ago by James Till and Ernest McCulloch, adult stem cells have been found in many more tissues than initially anticipated, including brain, bone marrow, fat, peripheral blood, blood vessels, skeletal muscle, skin, teeth, heart, gut, liver, ovarian epithelium and testis. ...
A recent study published by the Proceedings of National Academy of Science has found that exposure to the chemical triclosan is linked to muscle function impairments. Triclosan is an antimicrobial agent typically found in products such as soaps, deodorants, toothpaste, mouthwash, clothes, bedding, carpet, toys, and trash bags. ...
In "test tube" experiments, triclosan impaired the ability of isolated heart muscle cells and skeletal muscle fibers to contract. Specifically, the team evaluated the effects of triclosan on molecular channels in muscle cells that control the flow of calcium ions, creating muscle contractions. ...