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Tissue Specific Articles & Analysis: Older
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Each tissue microarray is constructed from paraffin-embedded (FFPE) tissue blocks from a specific number of donor cases. Additionally, the microarrays come in various configurations, with a range of cases and core numbers per case, allowing researchers to tailor their experiments to their specific needs. For example, the Multiple ...
By encapsulating active pharmaceutical ingredients (APIs) within these microspheres, drugs can be delivered directly to specific tissues or organs, resulting in improved therapeutic efficacy and reduced side effects. ...
These drug delivery systems can enhance the interaction with biological materials and conjugate to specific target molecules to reach specific tissues or cells by modifying their surface properties. ...
ITM-31 is a carbonic anhydrase XII (CA XII)-specific antibody Fab fragment developed by Helmholtz Munich and coupled with ITM's medical radioisotope, non-carrier-added Lutetium-177 (n.c.a. 177Lu, EndolucinBeta®). ...
The majority of PROTACs were created with ligands that recruit E3 ligases, which are widely expressed in tumors and normal tissues, and these PROTACs can cause off-target toxicity if the target protein is not tumor-specific. The development of tumor-specific/selective PROTACs will benefit from identifying those E3 ligases that are enriched in ...
The Elucid platform is the only FDA-Cleared and CE-Marked software to objectively quantify plaque morphology validated against tissue specimens. Specifically, the exquisite algorithms developed through machine learning characterize tissue types in the artery wall known to cause heart attacks, such as lipid rich necrotic core. ...
ByElucid
It is recommended to determine 50% cytotoxicity concentration (CC50) values in quiescent and to divide cells from various relevant human cell types and tissues to ascertain the potential for cell cycle, species, or tissue-specific toxicity. ...
Co-stimulatory agents, like 4-1BB agonists, are known as accelerators of cancer immunotherapy, because they help induce potent, tumor-specific T-cells that can infiltrate and kill tumors. The combination of an arenaviral immunotherapy with a 4-1BB agonistic antibody resulted in complete tumor rejection in 30 percent of mice following treatment. ...
Whole transcriptome refers to the sum of all RNA (transcripts) transcribed from a specific species, tissue or cell type under a certain period or condition, including mRNA and non-coding RNA (ncRNA). ...
It is concentrated in CG-rich regions and regions immediately downstream of translation initiation sites and has conversed, and has the characteristics of conservation, tissue-specific and dynamic features across mammalian transcriptomes. ...
New results from the OMICS study, which will be presented atASCO, show Universal DX's blood test can detect colorectal cancer with extraordinary accuracy (92% sensitivity / 97% specificity), which exceeds currently available non-invasive tests for colorectal cancer screening Early detection cancer screening via a liquid biopsy is not only critical to save lives, but is a vast ...
TISSIUM, a privately-owned medtech company developing biomorphic programmable polymers for tissue reconstruction, announced today it has been named a French Tech 120 company for the 2021 program. ...
ByTISSIUM
TISSIUM, a privately-owned life science company developing fullysynthetic, biomorphic programmable polymers, announced today it has been awarded 2.2M€ in financing that will accelerate its development of a drug-eluting tissue adhesive to address the unmet needs of Chronic Rhinosinusitis (CRS) patients. ...
ByTISSIUM
Slawin, Founder and Managing Partner of Rapha Capital Management, previously founded Bellicum Pharmaceuticals, a NASDAQ-traded cellular immunotherapy company. 3DBio Therapeutics is advancing therapeutic-grade bioprinting to manufacture living tissues designed and created specifically for each individual patient. ...
Without complete pathology results and sufficient tissue for specific therapy tests, oncologists have no choice but to prescribe broad chemo-radiation therapy, which can cause serious side effects. “The primary advantage of the UA design is its ability to scoop tissue from beyond the confines of the needle, collecting seven times the ...
Hockey for Heroes, a supporting charity of Help for Heroes who raise money to help our injured and fallen Heroes, today announces a multi-thousand pound sponsorship renewal with Celixir, a leading British Cell Therapy company. Celixir continues as the charity’s main shirt sponsor for 2018-19, enabling Hockey for Heroes to expand its program to enable injured veterans to take part in ...
” “CTL’s in-house technology focuses on the discovery of novel tissue-specific cellular medicines. We are delighted that Daiichi Sankyo share our belief in iMP cells’ potential in heart regeneration,” commented Professor Sir Martin Evans, Nobel Laureate and CTL’s Chief Scientific Officer. ...
Adult stem cells are undifferentiated cells, found throughout the body after embryonic development, which multiply by cell division to replenish dying cells and regenerate damaged tissue. Adult stem cells support tissue and organ turnover throughout life by maintaining a delicate balance between apoptosis and tissue-specific ...
This specification covers the raw material and final product requirements, and the associated test methods for the selection of porous high density and ultra high molecular weight polyethylenes intended for use in surgical implants. ...