Vascular Inflammation Articles & Analysis
6 news found
Pulmonary arterial hypertension (PAH) is a progressive, life-threatening condition characterized by increased pulmonary arterial pressure, vascular remodeling, and persistent inflammation. Despite advances in treatment, current therapies—such as sildenafil, iloprost, and riociguat—primarily focus on reducing symptoms by dilating blood vessels. ...
” It is well established that neurovascular dysfunction, blood–brain barrier (BBB) leakage, and persistent vascular- and neuro-inflammation are among the critical events that eventually lead to neurodegeneration. ...
"Gesynta Pharma has already shown that GS-248 exerts strong effects on biomarkers of inflammation and vascular protection in humans, and we are excited to now initiate a Phase II study in patients with systemic sclerosis. ...
The confirmation of strong effects on biomarkers of inflammation and vascular protection in humans demonstrates the potential of GS-248 as a unique treatment of microvascular dysfunction in Systemic Sclerosis and other chronic inflammatory conditions. ...
The confirmation of strong effects on biomarkers of inflammation and vascular protection in humans demonstrate the potential of GS-248 as a unique treatment of microvascular dysfunction in Systemic Sclerosis and other chronic inflammatory conditions." says Patric Stenberg, CEO of Gesynta Pharma. ...
Published in today's edition of the online journal 'Genome Biology,' the study is the first to explain how fine particles in air pollution work with artery-clogging fats to switch on the genes that cause blood vessel inflammation and lead to hardening of the arteries and cardiovascular disease. ...