Miroculus to Optimize Automated Next Generation Sequencing Library Preparation with Interpace Diagnostics and Twist Bioscience

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May. 10, 2022

Interpace Biosciences, Inc. (OTCQX: IDXG) (“Interpace” or the “Company”), a leader in enabling personalized medicine, has announced that in association with Miroculus, Inc., a developer of revolutionary tools for personal lab automation, it will optimize next generation sequencing (NGS) library preparation utilizing its digital microfluidics (DMF) technology. Also working in conjunction with Miroculus and Interpace Biosciences will be Twist Bioscience Corporation (NASDAQ: TWST), a company enabling customers to succeed through its offering of high-quality synthetic DNA.

“We are excited to work alongside Interpace Diagnostics and Twist Bioscience in providing better solutions in cancer diagnostics for patients and patients’ families,” said Alejandro Tocigl, Miroculus CEO. “The Miro Canvas offers a truly ‘walk away’ solution for complex NGS workflows without the need to batch samples together.”

Interpace Diagnostics will utilize Twist Bioscience’s chemistries for library preparation and hybridization capture for the automation of Interpace’s custom NGS panels, and Miroculus’s DMF instrument, the Miro Canvas, to enable low volume, accurate, and precise sample preparation for its genetic tests targeting specific markers in Endocrine and GI cancers. This work will minimize the requirement for hands-on technician time and accelerate implementation of diagnostic testing and assessment for patients living with or who are predisposed to the development of aggressive and difficult to treat forms of these cancers.

“Our goal is to transform our CLIA laboratory into a high throughput, state of the art automated facility, and our adaptation of cutting-edge technology from Twist Bioscience and Miroculus is driving this transformation,” said Alidad Mireskandari, Ph.D., M.B.A. Chief Development Officer of Interpace Biosciences. “We look forward to adopting our partners’ technology into our clinical operations to drive productivity and reduce costs as the value of their technology solutions become more evident in our validation work.”

“It’s an exciting time in diagnostic testing as new insights are unveiled every day that allow patients to be treated earlier in their cycle of disease. We are pleased to enable Interpace’s deployment of clinical services with our flexible sample-to-sequencer NGS reagent workflow that improves the uniformity of their assays, thus reducing the cost of sequencing and the assay overall,” commented Emily M. Leproust, Ph.D., CEO and Co-founder of Twist Bioscience.

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