PERKINELMER AND UNIVERSITY OF COPENHAGEN ANNOUNCE LICENSING AGREEMENT FOR IMPORTANT NEW MATERNAL HEALTH MARKER ADAM12

Marker Has Strong Potential to Improve Prenatal Risk Assessment Through Enhanced Detection of Chromosomal Abnormalities and Diseases of Late Pregnancy

BOSTON – PerkinElmer Inc. (NYSE: PKI), a leading provider in genetic screening, drug discovery, life science research, and analytical solutions, has entered into a global licensing agreement with the University of Copenhagen in Copenhagen, Denmark, to develop assay kits for the biochemical marker ADAM12. ADAM12 has broad potential in maternal health screening as a marker for fetal chromosomal abnormalities as well as for intrauterine growth retardation (IUGR) and pre-eclampsia, both of which can result in, maternal, fetal and long-term complications if left undiagnosed.

The license agreement covers exclusivity in North America and co-exclusivity in Europe , Central and South America . Kits will be developed for the complete portfolio of PerkinElmer platforms, including AutoDELFIA, DELFIA Xpress and manual DELFIA platforms.

“We are very excited about the potential of this marker for improving the performance of prenatal risk assessment,” said Ann-Christine Sundell, vice president and general manager, Genetic Screening, PerkinElmer. “The inclusion of ADAM12 with other existing biochemical markers in both the first and second trimester of pregnancy is expected to offer enhanced detection and reduced false positives, therefore decreasing the need for invasive diagnostic testing, which carries an associated procedural loss rate often quoted as one percent.”

“The University of Copenhagen is very pleased to announce the agreement with PerkinElmer. Our technology transfer unit was established to make sure that the University's most promising research results are commercialized in collaboration with companies who will be able to bring them to the market in an efficient and responsible way,” said Ralf Hemmingsen, dean at the Faculty of Health Sciences, University of Copenhagen. “The dialogue with PerkinElmer has been very constructive and we find it immensely encouraging that research performed in Copenhagen will form the basis of a product that can be of benefit to pregnant women.”

A team consisting of Dr. Ulla Wewer at the University of Copenhagen, Dr. Michael Christiansen from Statens Serum Institut (SSI) and Dr. Kevin Spencer at the Harold Wood Hospital in England have done all of the groundwork and tested ADAM12 in several thousand samples from pregnant women to investigate its importance for prediction of chromosomal disorders.

ADAM12 also shows potential to provide an early indicator of IUGR and pre-eclampsia, for which there are no current screening mechanisms. Early studies at the University of Copenhagen , SSI and Harold Wood have shown that ADAM12 levels were reduced at 10-14 weeks in pregnancies that developed pre-eclampsia and were greatly reduced in those exhibiting both pre-eclampsia and low birth weight.

“Pre-eclampsia and other hypertensive disorders of pregnancy are a leading global cause of maternal and infant illness and death,” said Sundell. “An early marker for this condition will provide the opportunity to investigate potential treatments at the early stage of the disease process and better manage the high-risk pregnancy.”

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PerkinElmer, Inc. is a global technology leader driving growth and innovation in Health Sciences and Industrial Sciences markets to improve the quality of life. The Company reported revenues of $1.7 billion in 2004, has 10,000 employees serving customers in more than 125 countries, and is a component of the S&P 500 Index. Additional information is available through www.perkinelmer.com or 1-877-PKI-NYSE.

For further information:
Investor Contact: Media Contact:
Dan Sutherby Stacey Holifield
PerkinElmer, Inc. Brodeur
(781) 431-4306 (617) 587-2026

University of Copenhagen :
Karen Laigaard
Head of Tech Transfer Unit
+45 35 32 70 54