Profacgen Provides Protein Ubiquitination Services to Accelerate Drug Development Project

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May. 27, 2022
Courtesy ofProfacgen

Profacgen, an experienced provider in biological research and drug discovery, provides various ubiquitin services to help customers accelerate research progress and obtain better results.

 

Ubiquitination is one of the most prevalent post-translational modifications (PTMs) in cells. Ubiquitin modification induces protein degradation, which affects the function, localization, and activity of proteins. Therefore, the study of protein ubiquitination plays an important role in cell biology and drug discovery.

 

With the comprehensive advanced platform, Profacgen offers its customers the following services:

 

In Vitro ubiquitin conjugation reactions

Profacgen provides services to perform ubiquitin reactions in vitro and analyze the results.

 

Assay to measure protein ubiquitination in living cells

Profacgen provides ubiquitin assays that can measure all types of ubiquitination on a target protein in living cells. With the help of bioluminescence resonance energy transfer (BRET) methods, customers are able to study the dynamic ubiquitination of target protein and understand which cellular functions are regulated by ubiquitylation.

 

Ubiquitin identification and quantification by proteomics analysis

Profacgen offers ubiquitin identification and quantification services for protein in cells or tissues. The work starts from enzymes digestion, peptides enrichment, mass spectrometry analysis and bioinformatics analysis.

 

Advantages of ubiquitination services offered by Profacgen

Rich and comprehensive services

Professional evaluation and experimental design

Stable platform and accurate data

Timely feedback on project progress

 

Moreover, to assist scientist better with their drug discovery research, Profacgen has established a comprehensive PROTAC technology platform and services including E3 Ligase and Target Proteins Development, Ligand Discovery and Design, PROTAC In Vitro and In Vivo Evaluations, and Targeted Protein Degradation.

 

“In addition, we have built a mature computer-aided drug design technology platform, which can greatly accelerate your research process. We offer customized and one-stop PROTAC development services and strive to solve all challenging obstacles during your PROTAC research.” Said Crystal, the chief marketing staff at Profacgen.

 

More detailed information about the custom protein ubiquitination service at Profacgen can be viewed here: https://www.profacgen.com/custom-protein-ubiquitination-services.htm.

 

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