The Effect of Combined Exercise and Diet on Obese Mice

Obesity is a metabolic condition resulting from an imbalance between the energy consumed and the energy expended. This is often caused by an increase in the intake of calorie-dense foods and a decrease in physical activity, leading to an abnormal build-up of fat. Such fat accumulation can have serious health consequences, raising the risk of chronic diseases like cardiovascular conditions, diabetes, and some cancers. It is usually associated with a higher prevalence of non-alcoholic fatty liver disease (NAFLD) and asthma.

While combining exercise and diet is majorly used as conservative measures in the treatment of obesity, a study by Marain NF et al.¹ highlighted the impact of intensive exercise and diet on the respiratory system and obesity-related parameters in mice.