Why small molecule development？

Small molecules play a crucial role in modern drug discovery and development. They are typically organic compounds with a low molecular weight that can easily penetrate cell membranes, making them ideal candidates for targeting intracellular pathways and interacting with specific proteins or enzymes. Small molecule drugs have a proven track record of success in treating a wide range of diseases, including cancer, cardiovascular disorders, and infectious diseases.

By leveraging the potential of small molecules, our clients can benefit from:

Targeted Therapies - Small molecules can be designed to selectively modulate specific biological targets, allowing for precise intervention in disease processes.
Oral Bioavailability - Many small molecules are suitable for oral administration, making them convenient and patient-friendly dosage forms.
Chemical Diversity - The vast chemical space of small molecules provides opportunities for lead optimization and the development of novel drug candidates.
Regulatory Success - Small molecules have a well-established regulatory pathway, facilitating the approval and commercialization process.
Areas covered by our small molecule development capabilities
Protheragen-ING Lab specializes in small molecule development and offer a comprehensive range of services to support the entire drug development process. Our capabilities cover the following areas:

Medicinal Chemistry
Our team of medicinal chemists designs and synthesizes novel small molecules to target specific diseases or biological pathways. We employ state-of-the-art techniques and technologies to optimize the potency, selectivity, and safety profiles of these compounds.
Analytical Chemistry
We have advanced analytical capabilities to characterize and analyze small molecules at every stage of development. Our analytical chemistry services include structure elucidation, impurity profiling, stability testing, and method development/validation, ensuring the quality and integrity of your small molecule candidates.
Formulation Development
Our formulation scientists work closely with our clients to develop optimal formulations for small molecules, ensuring their stability, solubility, and bioavailability. We have expertise in various formulation types, including tablets, capsules, injectables, and topical preparations.
Process Development and Scale-up
We provide process development and scale-up services to facilitate the manufacturing of small molecule active pharmaceutical ingredients (APIs) and preparations. Our team of chemical engineers and process chemists optimize synthetic routes, develop efficient manufacturing processes, and scale them up for commercial production.