In Vivo Models Services For Pre-Clinical
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Manufactured by SynVivo, Inc.based in USA
The SynVivo platform has been validated for accurate prediction of in vivo responses. Use this unique in vitro platform for realistic assessment of drug delivery, analysis of cell-cell, cell-drug, and their underlying mechanisms. Recreate cellular and tissue architecture in a Organ-on-Chip format compatible with standard analytical instrumentation. With simultaneous visualization and real-time ...
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by SoBran Inc.based in USA
Our scientific and technical experts assemble customized research programs with attention to your specific project requirements, timelines and budget. To support small animal preclinical toxicology and drug discovery, we offer an expanding range of services that meet GLP and non-GLP compliant in vivo research requirements. Program management is certified to the ISO 9001:2008 standard. ...
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Manufactured by Creative Bioarraybased in USA
Embryonic stem cells (ESCs) are abbreviated as ES, EK, or ESC cells. They are a class of cells isolated from early embryos (before the proto-intestinal stage) or primitive gonads, which have the properties of unlimited proliferation, self-renewal and multidirectional differentiation in vitro in culture. ES cells can be induced to differentiate into almost all cell types of the organism, both in ...
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by Oncodesignbased in FRANCE
Establishing proof of concept in preclinical pharmacology is a critical step in the drug discovery process. This is one of the decisive factors in setting the therapeutic indication(s) targeted in clinical models and in the decision to continue a new product through the regulatory preclinical and clinical steps. For more than 25 years, Oncodesign has been a player known for its experience and ...
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Manufactured by Newcells Biotech Limitedbased in UNITED KINGDOM
Cross-species comparison of drug handling with near-physiological kidney transporter model. New drug molecules are usually tested in vivo in two preclinical species to gain a more detailed understanding of how they are transported and eliminated through the kidney and also to mitigate risk of renal toxicity in humans. However, these animal models are not always predictive of human responses. To ...
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Manufactured by ReGen Therapeutics Limitedbased in UNITED KINGDOM
During ReGen’s discussions with potential licensing partners in 2004, it became apparent that a product based on the Colostrinin™ complex, as a whole, was more commercially attractive as a nutraceutical, rather than as a pharmaceutical. It was decided, therefore, to develop the original formulation of Colostrinin™ as a ...
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Manufactured by Inovotion Sasbased in FRANCE
Pharmaceutical chemical and biology researchers need to develop new methods and models to improve the predictivity of preclinical discovery phases and increase the number of good molecules in clinic. INOVOTION’s unique in vivo technology will allow you to raise the global number of drug candidates tested in clinic without increasing your ...
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by Selvita S.A.based in POLAND
Having experience in both pharma and biotech R&D, we are well aware of what it means to discover a hit and transform it into a drug. You can best benefit from this “insider” experience through our integrated drug discovery services built ...
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based in USA
Extrachromosomal arrays enable your desired construct to be expressed without being integrated into the genome. Using extrachromosomal arrays, you can choose to express a variety of configurations of transgenes, such as ...
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Manufactured by Creative Biolabsbased in CHINA
The construction of an antibody-drug conjugate (ADC) is the covalent coupling of a monoclonal antibody and a toxic payload drug via a linker molecule. The ultimate goal for an ADC development project is to deploy the resulted ADC into in vivo systems, both in model animals and eventually human patients, to cure cancer and other diseases utilizing its payload ...
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Manufactured by Creative BioMartbased in USA
Creative Biomart provides drug analysis service for pre-clinical drugs and natural products on their physical and chemical properties. Our services include three main assays: pre-clinical pharmaceutical property analysis, pharmacokinetics analysis & bioanalysis, andnatural product ...
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Manufactured by Charles Riverbased in USA
From complete IND-enabling programs to stand-alone assessments, our Safety Assessment team provides a full range of in vivo and in vitro testing services and regulatory support to comply with worldwide regulatory restrictions for the nonclinical development of pharmaceuticals, medical devices and animal health products as well as chemicals, agrochemicals, and biocides. Our scientific and ...
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based in USA
Battelle is a global leader in the pharmaceutical and biotechnology (BioPharma) industry by virtue of our integrated scientific and technological capabilities, world-class facilities and the ability to meet the unique technical, development and regulatory needs of global pharmaceutical companies and government health ...
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Manufactured by Ozgene Pty Ltd.based in AUSTRALIA
Humanized mice broadly refers to mice expressing human genes via transgenesis to gain relevant insights in the in vivo context for the understanding of human-specific physiology and pathology. Whilst many basic biological insights have been obtained from mouse studies, there are limitations to mouse models when investigating human biology. There are components of mouse biology systems that are ...
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Manufactured by Arthus Biosystems, LLCbased in USA
S-adenosylmethionine (SAM) is an important molecule in methionine cycle pathway and one carbon metabolism pathway that are implicated in many metabolic abnomalities found in humans. Methylation index is defined as the ratio of SAM and SAH, which is a better way to evaluate methylation status of humans and other organisms. The level of S-adenosylmethionine (SAM) fluctuates depending on age, ...
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Manufactured by Nexelisbased in USA
Custom In Vivo Models and Testing Solutions. Selecting the appropriate in vivo model for your assays is critical for the success of your preclinical research program. At Nexelis, a Q² Solutions Company, we designed and developed disease specific in vivo models alongside bespoke personalized model development services. Our wealth of experience and capabilities allows us to help answer our ...
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Manufactured by Charles Riverbased in USA
Discovering and characterizing novel drug candidates for preclinical development depends on innovative and reliable science. Our unique combination of integrated, multidisciplinary drug discovery expertise and unparalleled scope of capabilities in targets, platforms, and therapeutic areas allow us to deliver depth and breadth in science with data and insight you can trust to progress your drug ...
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Manufactured by InnoSer Belgie NVbased in BELGIUM
We offer multi-validation solutions for preclinical targets across numerous therapeutic fields. ...
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Manufactured by LVD Biotechbased in SPAIN
Capability to test our manufactured products in vivo in swine ...
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Manufactured by Nexelisbased in USA
Custom Assay Development to Advance Molecules. You need reliable approaches to support what’s next in your development programs whether they are complex small molecules, advanced biologics, or vaccines. At Nexelis, a Q² Solutions Company, we break down barriers to translational research through innovation and collaboration, helping you deliver better treatments to more patients, ...
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