Preclinical Drug (Preclinical Drug) Equipment
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by Verb Bioticsbased in USA
Yso3 is a preclinical drug development program aimed at treating asthma. Using a revolutionary form of living biotherapy targeting the lung, YSOPIA is pioneering the innovative field of the lung microbiome. As part of this program, YSOPIA has selected a clinical candidate having demonstrated strong in vivo efficacy on inflammation and ...
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Manufactured by Emulatebased in USA
Investigate mechanisms of toxicity for preclinical drug candidates to help decrease clinical trial safety failures. Drug-induced liver injury (DILI) is a primary concern during drug development that remains poorly understood due to species differences in liver toxicity and the limited predictivity of conventional in vitro models. ...
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Manufactured by 3B Pharmaceuticals GmbHbased in GERMANY
Discovery and preclinical development of peptide drug candidates have been 3BP’s core competencies since the company’s inception. ...
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based in USA
Utilizing our proprietary Sword Swift™ Method Development Process and Sword Swift™ Detection Reagents, our scientists can develop sensitive quantitative assays to measure the amounts of free or bound drug in preclinical or clinical samples with high accuracy and ...
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Manufactured by CytomX Therapeutics, Inc.based in USA
CytomX is developing CX-2009, a Probody drug conjugate (PDC) conjugated with DM4, a highly potent cytotoxic drug, targeting CD166, also known as ALCAM. CD166 is a molecule widely and highly expressed on solid tumor cells and previously considered “undruggable” given its expression on normal tissues. In preclinical studies, ...
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Manufactured by Emulatebased in USA
combines primary human cells in a dynamic microenvironment for an improved model of the proximal tubule-peritubular capillary interface. Applications include preclinical toxicity testing of drug candidates across a diverse array of ...
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Manufactured by Confo Therapeuticsbased in BELGIUM
Confo Therapeutics is building a pipeline of drug candidates with the potential to transform therapeutic outcomes for patients with severe illnesses lacking disease-modifying ...
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Manufactured by Addex Therapeuticsbased in SWITZERLAND
Our partnered drug candidate, ADX71149 is a novel orally active mGlu2 PAM for the treatment of epilepsy. Our partner, Janssen Pharmaceuticals, Inc., or Janssen, a subsidiary of Johnson & Johnson is conducting a placebo- controlled Phase 2a proof of concept clinical trial of ADX71149 in epilepsy patients since June 2021. We expect the ...
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Manufactured by Bmseedbased in USA
Mechanics Module: strain rate up to 1/s, strain up to 20%. Imaging Module: frame rate: 150fps. Electrophysiology Module: 2x60 channels. Physiological stretch of cells to reproduce the environment of cells inside the body; assessment of cell health, function, and maturity using electrophysiological measurements; visualization of cells and cellular processes during ...
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Manufactured by SiO2 Materials Sciencebased in USA
We provide a common drug contact surface starting at the research and pre-clinical drug development phases, through clinical trials, and on through to commercial ...
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Manufactured by SiO2 Materials Sciencebased in USA
We provide a common drug contact surface starting at the research and pre-clinical drug development phases, through clinical trials, and on through to commercial ...
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Manufactured by Ncardia Services B.V.based in NETHERLANDS
The discovery that transformed biological research. In 2007, Shinya Yamanaka and Kazutoshi Takahashi were able to reprogram human somatic cells into pluripotent stem cells by inducing the expression of four embryonic transcription factors. The resultant cells were called human induced pluripotent stem cells (iPSC). iPSCs have unlimited proliferation capacity and can be differentiated into nearly ...
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Manufactured by DCN Dxbased in USA
The Capitainer qDBS is the most accurate and consistent at-home blood sampling device—perfect for high-throughput applications. The Capitainer qDBS enables convenient, at-home, unassisted collection of a precise blood volume and eliminates the risk of over or under-filling. The simple design reduces the likelihood of human error during blood sampling via fingerstick and does not require ...
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based in USA
Flu – A Serious, Deadly Disease with Pandemic Potential. In 1918, the Spanish flu (H1N1 influenza virus) rapidly killed 50 to 100 million people worldwide, affecting one of every five Americans. Today, influenza remains a common and serious respiratory illness that contributes to the reduction of quality of life and results in a significant loss of manpower hours each year. Every year, 40 ...
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Manufactured by Qualigen Therapeutics, Inc.based in USA
Our RAS-F portfolio includes lead and back-up small molecules that suppress the interaction of endogenous RAS with c-RAF, upstream of the KRAS, HRAS, and NRAS effector pathways. This potentially enables a differentiated, RAS-targeted strategy for inhibiting the MAPK, PI3K, and TOR pathways that are implicated in cancer cell proliferation, survival, and differentiation (see figure). RAS itself ...
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Manufactured by InMed Pharmaceuticals Inc.based in CANADA
INM-755 is a cannabinol topical cream under development for the treatment of epidermolysis bullosa. INM-755 cream for EB is the first, and currently the only, cannabinol formulation being tested in clinical trials as a therapeutic ...
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