CD Formulation Pre-Clinical Services
-
Manufactured by CD Formulationbased in USA
Antibacterial, anti-inflammatory, and antiviral drugs are commonly used clinically. However, with the spread and evolution of drug resistance, the efficacy of these drugs, especially antibacterial and antiviral drugs, is declining. At present, there is no effective means to deal with the problem of drug resistance clinically, and the development of new drugs is urgently needed. CD Formulation ...
-
Manufactured by CD Formulationbased in USA
Solubility and bioavailability issues run through drug metabolism and pharmacokinetic evaluation of candidate compounds, preclinical prescription development, and commercial formulation development. From the toxicological evaluation stage, CD Formulation has a perfect drug metabolism and pharmacokinetic support system, each experiment only consumes milligram-level API, which can help customers ...
-
Manufactured by CD Formulationbased in USA
The Main Objectives of Conducting Forced Degradation Tests Include: Resolve the degradation products and determine the degradation pathway and mechanism of the drug. Help the development of API processes, formulation prescriptions and processes, and to help the screening of drug salts and crystalline forms. Provide support for drug safety. Guide the development of drug packaging systems and to ...
-
Manufactured by CD Formulationbased in USA
CD Formulation researchers have conducted extensive research and development of drug delivery systems (DDS) in order to improve the pharmacokinetics and pharmacodynamics of drugs by delivering the required dose at the target site at the appropriate time and rate. Our drug delivery system development offerings include nanoparticles and particles, transdermal patches, and more. Our current services ...
-
Manufactured by CD Formulationbased in USA
At present, many drugs are often lower than the concentration required for treatment due to their low solubility, even in saturated solutions. For example, the solubility of chloramphenicol in water is 0.25%, and clinically, more than 12.5% solution is required for intramuscular or intravenous injection. In the pharmaceutical liquid preparation industry, it is necessary to increase the solubility ...
-
Manufactured by CD Formulationbased in USA
Swelling Performance Evaluation for Microspheres & Microneedles: Swelling test is one of the basic testing methods for microneedles and microspheres material properties. The purpose is to test the ability of microneedles and microspheres materials to absorb or release drugs as substrates for sustained drug release systems. The swelling tests of microspheres and microneedles are provided by CD ...
-
Manufactured by CD Formulationbased in USA
CD Formulation has a team of experienced transdermal drug delivery professionals and cutting-edge transdermal drug delivery technologies, and can provide customers with CRO services for microneedle drug development, transdermal drug delivery solutions and technical support for process optimization. We can provide personalized, multi-faceted, differentiated and customized services for the ...
-
Manufactured by CD Formulationbased in USA
Preparation of Nano-vesicles for Encapsulating Protein Drugs: CD Formulation can customize the vesicles that encapsulate protein drug molecules to avoid the technical problems of drug rupture and leakage during in vivo delivery. Our technical team will perform a full range of analytical tests to ensure that the product meets your requirements and helps you develop your ...
-
Manufactured by CD Formulationbased in USA
Bioavailability of active pharmaceutical ingredients (APIs) is a key factor in successful drug development. By choosing API physical modification services, we can support your solution, improve poor water solubility, and control optimized release characteristics to help increase your productivity and return on investment. Nanomilling to Prepare Small Particle Size Drug Particles Services ...
-
Manufactured by CD Formulationbased in USA
Molar Concentration of Osmotic Pressure Test: Based on CD Formulation's professional laboratory equipment and scientific staff, we provide professional testing services for osmolality molar concentration, which also includes the determination of osmolality molar concentration ratio. By testing the above mentioned drug parameters, we can effectively help our customers to develop drugs faster and ...
-
Manufactured by CD Formulationbased in USA
Poor solubility and low bioavailability of drugs are an important link that affects drug development. CD Formulation provides a variety of ways to improve these shortcomings of drugs, including physical and chemical methods. Among them, physical modification methods include eutectic method in addition to nano-grinding and micronization. Co-crystal refers to the crystal formed by the combination ...
-
Manufactured by CD Formulationbased in USA
CD Formulation's Contract Development and Manufacturing (CDMO) division is a leader in drug development and drug delivery pathway development, offering services such as bioresorbable particle system development. CD Formulation also offers integrated services from evaluation of drug formulation to drug product development, scale-up production, and commercial manufacturing, our pharmacy experts ...
-
Manufactured by CD Formulationbased in USA
Industry estimates indicate that over 80% of new chemical entities exhibit low solubility, low bioavailability, and/or low or inconsistent dissolution rates. Effectively addressing these drug solubility, bioavailability, and dissolution rate issues is critical to advancing compound development and providing patients with the therapeutic benefits needed for pharmaceutical products. The Enhanced ...
-
Manufactured by CD Formulationbased in USA
About 40% of newly developed medicinal chemical entities have poor water solubility, and 90% of drugs under development can be classified as poorly soluble drugs. A solid dispersion (SD) refers to a dispersion system in which the drug particle size is within the range of 0.001 to 0.1 μm in a certain state and uniformly dispersed in a solid carrier. As an intermediate of pharmaceutical ...
-
Manufactured by CD Formulationbased in USA
The residue on ignition check method is used as an indicator to control the quality of API. CD Formulation offers a professional drug residue on ignition test, which assesses the quality of a drug by heating the drug to char and then ashing it. CD Formulation's business covers all aspects of drug formulation, drug ingredients, drug development, drug testing, drug optimization, etc. ...
-
Manufactured by CD Formulationbased in USA
Analytical Methodology Research: CD Formulation is dedicated to the development of services for pharmaceutical formulations, including physicochemical property testing, impurity testing, biological testing, stability analysis, etc. However, the development of these test methods requires validation, and only after validation can we guarantee reliable, accurate and precise test results. In our ...
-
Manufactured by CD Formulationbased in USA
Long-term accelerated shelf-life testing is performed in artificial environments where the temperature and humidity exceeds normal conditions of sale and consumption. After accelerated aging testing, the product must be subjected to the necessary physical, microbiological and chemical analyses to ensure that we have prior knowledge of the product's stability. CD Formulation offers rapid aging ...
-
Manufactured by CD Formulationbased in USA
Microsphere Development: Among the many existing extended release formulations, microspheres have unique advantages such as gradual release of the drug by degradation of the microspheres after administration, avoidance of blood concentration peaks and valleys, reduction of the dose during the therapeutic cycle, and improvement of the bioavailability of the drug and patient compliance. CD ...
-
Manufactured by CD Formulationbased in USA
One-Stop Solution for Small Molecule Drug Formulation: Small molecule drugs are chemically synthesized small molecules of active substances. Small molecule components can be made into tablets or capsules that are easily absorbed by the body. CD Formulation has extensive research experience in drug formulation development and is committed to providing efficient, flexible and high-quality one-stop ...
-
Manufactured by CD Formulationbased in USA
Nanoparticles have a high surface area to volume ratio, which allows them to hold a lot of material on their surface. When used as nanodrug carriers, the delivery of water-insoluble drugs is improved by delivering small particle size drugs that dissolve faster in the blood stream, resulting in targeted drug delivery in a cell- or tissue-specific manner. Carriers used for drug delivery include ...
Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you