- Home
- Companies
- MedChemExpress LLC (MCE)
- Products
- MedChemExpress - Model ...
MedChemExpress - Model Diethylcarbamazine citrate - 1642-54-2
Diethylcarbamazine citrate is an orally active anthropoidal compound. Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism of filaria microfilaria. Diethylcarbamazine citrate has anti-inflammatory and antiparasitic activity[1][2][3].MCE products for research use only. We do not sell to patients.
Diethylcarbamazine citrate
MCE China:Diethylcarbamazine citrate
Brand:MedChemExpress (MCE)
Cat. No.HY-12642
CAS:1642-54-2
Purity:99.95%
Storage:4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Shipping:Room temperature in continental US; may vary elsewhere.
Description:Diethylcarbamazine citrate is an orally active anthropoidal compound. Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism of filaria microfilaria. Diethylcarbamazine citrate has anti-inflammatory and antiparasitic activity.
In Vivo:Diethylcarbamazine citrate (250 mg/kg intravenously, single dose) induces a sharp early decrease in mf count in albino-infected rats, followed by an increase[2]. Diethylcarbamazine citrate (50 mg/kg orally, twice weekly) can improve insulin resistance in obese mice induced by high-fat diet by regulating adipose tissue inflammation[3].
Hot selling product:Dobutamine (hydrochloride) | Ranitidine (hydrochloride) | 20-Deoxyingenol | Eplerenone | Sabutoclax | Sofosbuvir | Stafib-1 | Lomustine | CCMI | Cleistanthin B
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
References:
[1]. El-Shahawi GA, et al. Setaria equina: in vivo effect of diethylcarbamazine citrate on microfilariae in albino rats. Exp Parasitol. 2010 Dec;126(4):603-10. [Content Brief]
[2]. Abdul-Razek N, et al. Enhancement of Anti-allergic Effect of Diethylcarbamazine Citrate in Asthmatic Mouse Model: Testing of Anti-drug Antibodies and Quercetin. Iran J Allergy Asthma Immunol. 2020 Aug 25;19(4):373-385. [Content Brief]
[3]. Abdel-Latif M. Diethylcarbamazine citrate ameliorates insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation. Int Immunopharmacol. 2015 Dec;29(2):607-612. [Content Brief]
Brand introduction:
• MCE (MedChemExpress) has a global exclusive compound library of more than 200 kinds, and we are committed to providing the most comprehensive range of high-quality small molecule active compounds for scientific research customers around the world;
• More than 50,000 highly selective inhibitors and agonists are involved in various popular signaling pathways and disease areas;
• The products cover a variety of recombinant proteins, peptides, commonly used kits, more PROTAC, ADC and other characteristic products, widely used in new drug research and development, life science and other scientific research projects;
• Provide virtual screening, ion channel screening, metabolomics analysis detection analysis, drug screening and other professional technical services;
• It has a professional experimental center and strict quality control and verification system;
• Provide LC/MS, NMR, HPLC, chiral analysis, elemental analysis and other quality inspection reports to ensure the high purity and high quality of products;
• The biological activity of the products has been verified by the experiments of customers in various countries;
• A variety of top journals such as Nature, Cell, Science and pharmaceutical patents have included the scientific research results of MCE customers;
• Our professional team tracks the latest pharmaceutical and life science research and provides you with the latest active compounds in the world;
• It has established long-term cooperation with the world's major pharmaceutical companies and well-known scientific research institutions。