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MedChemExpress - Model Catechin 7-O-ß-D-glucopyranoside - 65597-47-9

Catechin 7-O-beta-D-glucopyranoside is an orally active natural product found in Ulmus davidiana and Paeonia obovata. Catechin 7-O-β-D-glucopyranoside shows antioxidant and anti-inflammatory activities, and attenuates mitochondrial dysfunction. Catechin 7-O-beta-D-glucopyranoside can be used in intestinal inflammatory disease research[1][2][3].

Catechin 7-O-β-D-glucopyranoside

MCE China：Catechin 7-O-β-D-glucopyranoside

Brand：MedChemExpress (MCE)

Cat. No.HY-N10587

CAS：65597-47-9

Purity：99.48%

Storage：4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Shipping：Room temperature in continental US; may vary elsewhere.

Description：Catechin 7-O-beta-D-glucopyranoside is an orally active natural product found in Ulmus davidiana and Paeonia obovata. Catechin 7-O-β-D-glucopyranoside shows antioxidant and anti-inflammatory activities, and attenuates mitochondrial dysfunction. Catechin 7-O-beta-D-glucopyranoside can be used in intestinal inflammatory disease research.

In Vitro：Catechin 7-O-β-D-glucopyranoside (10 μg/mL; 24 h) shows protective effect against Streptozotocin-induced cell damage by its antioxidant effects and the attenuation of mitochondrial dysfunction[3].

In Vivo：Catechin 7-O-β-D-glucopyranoside (intraperitoneal injection; 10 mg/kg; once) treatment shows mild protective effect against lethality induced by LPS/D-GalN[1]. Catechin 7-O-β-D-glucopyranoside (oral administration; 10 mg/kg; once daily; 7 d) treatment prevents intestinal inflammatory damages in TNBS model of rat colitis[2].

References：

[1]. Zheng MS, et al. Protective constituents against sepsis in mice from the root barks of Ulmus davidiana var. japonica. Arch Pharm Res. 2011 Sep;34(9):1443-50. [Content Brief]

[2]. Kook SH, et al. Catechin-7-O-β-D-glucopyranoside isolated from the seed of Phaseolus calcaratus Roxburgh ameliorates experimental colitis in rats. Int Immunopharmacol. 2015 Dec;29(2):521-527. [Content Brief]

[3]. Kim KC, et al. Cytoprotective effects of catechin 7-O-β-D glucopyranoside against mitochondrial dysfunction damaged by streptozotocin in RINm5F cells. Cell Biochem Funct. 2010 Dec 2;28(8):651-60. [Content Brief]

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