Alucent - Revolutionary Treatment Technology for Peripheral Artery Disease (PAD)
PAD is a common circulatory problem in which narrowed arteries reduce blood flow to the extremities – generally affecting one or both legs. It is caused when the inner lining of arteries located outside of the heart get damaged by factors such as smoking, obesity, high blood pressure, elevated cholesterol, elevated triglyceride levels, and/or diabetes. Once vessels are damaged, plaque can form and build up, which causes arteries to narrow (atherosclerosis). The most common symptom of PAD is leg pain which can range from mild discomfort to debilitating pain – making walking and other physical activities difficult.
Treating PAD: An Unmet Need
Many medical devices have been developed in recent decades to treat PAD. The most commonly used treatments include angioplasty, stenting, and drug-coated devices. However, an unmet need still exists for PAD treatment because of the failure rates and need for reintervention or operation associated with these therapies.
Studies have shown that balloon angioplasty and stenting have high failure rates after only a year or two in patients with PAD. Stenting the arteries that pass through the knees can also be problematic due to a high risk of complications stemming from stent fracture, artery damage, and implant-related artery inflammation that leads to arterial re-narrowing and a need for re-treatment.
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