Model pTyr1234 - Anti-c-Met Antibody

Storage Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide *Storage buffer may change when conjugated

Storage Temperature: -20ºC, Conjugated antibodies should be stored at 4ºC

Shipping Temperature: Blue Ice or 4ºC

Purification: Peptide Affinity Purified

Clonality: Polyclonal

Isotype: IgG

Specificity: Detects endogenous levels of c-Met only when phosphorylated at tyrosine 1234 (pTyr1234). Detects a band at ~145 kDa.

Cite This Product: StressMarq Biosciences Cat# SPC-1400D, RRID: AB_2728925

Alternative Names: MET Antibody, Proto-oncogene c-Met Antibody, Met proto-oncogene (hepatocyte growth factor receptor) Antibody, HGF/SF receptor Antibody, AUTS9 Antibody, D249 Antibody, Oncogene MET Antibody, Met protooncogene Antibody, Par4 Antibody, MET proto oncogene, receptor tyrosine kinase Antibody, HGF Antibody, RCCP2 Antibody, Scatter factor receptor Antibody, SF receptor Antibody, HGFR Antibody, Tyrosine-protein kinase Met Antibody, MET_HUMAN Antibody, Met proto oncogene tyrosine kinase Antibody, Met proto-oncogene Antibody, Hepatocyte growth factor receptor Antibody, EC:2.7.10.1 Antibody, c met Antibody, HGF receptor Antibody

Research Areas: Cancer, Cell Signaling, Epigenetics and Nuclear Signaling, Growth Factor Receptors, Oncoproteins, Protein Phosphorylation, Receptor Tyrosine Kinases, Transcription, Tumor Biomarkers, Tyrosine Kinases

Cellular Localization: Basal Plasma Membrane, Cell Surface, Extracellular Region, Integral Component Of Membrane, Integral Component Of Plasma Membrane, Intracellular, Membrane, Plasma Membrane, Secreted, Single-Pass Type I Membrane Protein

Accession Number: NP_000236.2

Gene ID: 4233

Swiss Prot: P08581

Scientific Background: The proto-oncogene c-Met product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor.