Advanced Medical Solutions Group plc

Antibiotic Regenerative Collagens

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Our antibiotic regenerative collagen portfolio combines the proven properties of collagen with the antibiotic protection1 of gentamicin across our range of sponges, foils and cones.

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What is collagen with antibiotics?

Collagen is the most abundant protein in the bodies of mammals and is the substance that holds the whole body together. It is found in the skin, bones and connective tissue, providing structure, support and strength.

When processed for use as a medical device, collagen has several beneficial properties. It is biocompatible, has a low toxic risk, is absorbable, has a low immunological response and is resorbed during tissue regeneration.

Our products are manufactured from naturally cross-linked, equine derived collagen and have a good safety profile.

How does collagen with antibiotics work for haemostasis and wound healing?

The body can regenerate lost or damaged tissue, and collagen products help to support and stimulate this process. Collagen is absorbable, meaning it can be broken down and assimilated by the body. In wound healing, collagen attracts new cells to the wound site, providing a scaffold for new tissue growth.

Collagen is a well known and established haemostat, mechanically triggering platelet activation, which starts the natural clotting process. Collagen is also highly absorbent and absorbs large quantities of fluid. This mechanical action allows the absorption of both blood products to aid haemostasis as well as debris, such as bacteria and fibrin deposits. The formed collagen fibrin matrix, acts as a scaffold for fibroblast growth.

Collagen foils are also approved for use as a temporary barrier to prevent adhesions between various tissue layers.

Collagen products containing antibiotics are protected against microbial colonisation and can be used in a wide range of indications.

Key features

  • Haemostatic
  • Highly absorbent
  • Antibiotic protection
  • Biocompatible
  • Implantable
  • Pliable
  • Absorbable

Product benefits

  • Easy to cut and adapt
  • Structurally stable
  • Ability to absorb large volumes of fluid
  • Antibiotic protection to protect the implant from infections

Clinical benefits

  • Effective haemostasis
  • Integration into surrounding tissues within weeks
  • Provides a scaffold for new cell growth