Cartherics -Autologous T cells
This technology arms the patient’s own T cells with CARs, which enable them to “seek and destroy” cancer cells.
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These autologous CAR-T cells are further enhanced by deleting genes which act as immune hand brakes.
The combination of CAR “knock-in” and immune suppressor gene “knock-out” enables the CAR-T cells to completely eradicate a model of human ovarian cancer in mice.
Cartherics is in the process of establishing a separate company to develop its autologous CAR-T cell products, with the focus on two imminent clinical trials: Cutaneous T Cell Lymphoma and relapsed ovarian cancer.