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Ceturegel -Model 40186 -Basement Membrane Matrix

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Ceturegel basement membrane matrix is a soluble basement membrane preparation extracted from EHS mouse tumors rich in extracellular matrix proteins. Ceturegel™ GFR (Phenol Red-Free&LDEV-Free) is a low growth factor matrix obtained after special treatment, which can effectively ensure the needs of some experimental operations that require low growth factors, such as experiments related to signaling pathways and growth factors.

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Ceturegel Matrix will have a certain color difference due to the concentration difference. After freezing and thawing, gently shake the reagent bottle to make the Ceturegel Matrix evenly dispersed. All operations should be carried out in a sterile environment, and the cap of the reagent bottle can be wiped with 70% ethanol and dried naturally. A pre-cooled pipette should be used to ensure that the Ceturegel Matrix is homogenized.

Cells can grow on the surface of the 0.5 mm thick Ceturegel matrix layer or within the 1 mm thick Ceturegel matrix. Over-diluted Ceturegel Matrix will form a non-glial protein layer that can be used for cell adhesion, but not for cell differentiation studies.

Ceturegel Matrix GFR LDEV-Free Matrix is a soluble basement membrane preparation extracted from EHS mouse tumors rich in extracellular matrix proteins. Its main components are laminin, type IV collagen, heparan sulfate proteoglycan (HSPG) and nestin, as well as growth factors such as TGF-beta, EGF, IGF, FGF, tissue plasminogen activator and other growth factors contained in EHS tumors themselves. Ceturegel™ GFR Matrix  is a low growth factor Matrix  obtained after special treatment, which can effectively ensure the needs of some experimental operations that require low growth factors, such as experiments related to signaling pathways and growth factors. At room temperature, it aggregates to form a biologically active three-dimensional matrix, which simulates the structure, composition, physical properties, and functions of the cell basement membrane in vivo, which is beneficial to the culture and differentiation of cells in vitro. It can be used for cell morphology, biochemical function, migration, Invasion and gene expression studies.

The three-dimensional culture matrix formed by Matrix can promote the adherence and differentiation of epithelial cells, hepatocytes, Sertoli cells, melanoma cells, vascular endothelial cells, thyroid cells, and hair follicle cells. Ceturegel Matrix can affect gene expression in three-dimensional cultures of murine hepatocytes and human mammary epithelial cells. At the same time, CeturegelTM Matrix can be used as a basic scaffold for various tumor cell invasion studies, an essential matrix for in vitro and in vivo studies of angiogenesis, and a three-dimensional scaffold for the growth of transplanted tumor cells in vivo animal models. Ceturegel™ Matrix also supports the regeneration of peripheral nerves and the differentiation of bovine fallopian tube epithelial cells.

YEASEN Matrix is a sterile product, does not contain phenol red, and has a concentration of 8~12 mg/mL, which meets various experimental requirements.

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Dry ice shipping. -20 ? storage, valid for two years.