Poietis
Poietis Poieskin - Bioprinted Human Full Thickness Skin Model
FromPoietis
Poieskin is a Human Full Thickness Skin Model entirely produced by 3D bioprinting. Poieskin consists of a dermal compartment composed of primary human fibroblasts embedded in a collagen I matrix overlaid by a stratified epidermis derived from primary human keratinocytes.
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Histological analyses show a remodeled dermis with neo-collagen I synthesis and an epidermis with at least 8 cell layers as well as a stratum corneum.
Poieskin® stains positive for human collagen I in the dermis, epidermal differentiation markers (cytokeratin 5, cytokeratin 10, filaggrin) and a dermo-epidermal junction marker (collagen IV).