SCIEX -Model PA 800 Plus -Biotherapeutics Characterization System
Perform consistent and compliant biotherapeutics characterization faster than ever. With the PA 800 Plus system, you can confidently safeguard the success of your biologics. Run multiple characterizations from a single system that biopharma labs depend on, and produce qualitative and quantitative analyses, with speed and confidence.
The PA 800 Plus is a robust analytical platform that can help you with:
- Monoclonal Antibody Applications
- Purity/Heterogeneity with Gold Standard CE-SDS in minutes
- Glycan Analysis with award-winning Fast Glycan Technology
- Charge Heterogeneity with fast and simple CZE or with hi-res cIEF
- Peptides and Proteins beyond mAbs
- Cell and Gene Therapy Applications
- Capsid Proteins Purity
- Nucleic Acid and Plasmid Analysis
- Multiple Applications, One Platform: Run multiple protein characterizations from a single system to improve your operational efficiency and effectiveness.
- Raw Unmanipulated Data: Have the confidence critical to both you and regulatory agencies for product submission and commercialization with raw, unmanipulated data.
- Reproducibility Matters: Get repeatable results with exclusive recirculating liquid coolant to control separation temperature precisely.
- Portability Matters: Easily transfer methods using robust, automated assays with proven portability ‐ ideal for global multi-user, multi-instrument.
Biologics Characterization Results You Can Trust
Characterize molecules, large or small, with industry and regulatory compliant capillary electrophoresis (CE) technology. It’s why every biopharmaceutical company with therapeutic IgGs currently on the market uses SCIEX CE systems in their bioanalytical processes.
Industry and Regulatory Proven CE Technology
The PA 800 Plus Pharmaceutical Analysis System is a robust analytical platform so you can have confidence in your data, without sacrificing speed.
Increase Efficiency
Running multiple assays on one platform simplifies staff training, maximizes ROI and reduces laboratory footprint.
Trust Your Assays
Extensive intercompany studies demonstrate the robustness of SCIEX capillary electrophoresis assays, encompassing CE-SDS, cIEF, CZE, and glycan analysis.
Simplify Compliance
The USP has included validated procedures and system suitability criteria for IgG Purity and heterogeneity analysis by capillary electrophoresis.
Maximize Sensitivity
Achieve as low as 0.01% impurity detection, with at least three orders of magnitude of impurity, with modular detection (UV, PDA, LIF)
Automated and Quantitative Analysis of Biotherapeutics
Generate highly reproducible data with PA 800 Plus quantitative and automated solutions. Our engineers have collaborated closely with biopharma development and QC groups experienced in biologics characterization to create assays that address your analytical challenges.
Protein Purity Analysis
Quantitative Protein Purity Analysis with SDS-Gel Capillary Electrophoresis
Glycan Analysis
Run glycans faster than HILIC with simplified sample preparation, rapid, high-resolution separations, and automated glycan identification.
Charge Heterogeneity
Conduct advanced capillary isoelectric focusing (cIEF) and hi-speed capillary zone electrophoresis (CZE) for charge heterogeneity analysis
Peptide/Protein Characterization
Analyze peptide and protein biotherapeutics beyond mAbs.
Cell and Gene Therapy
Easily analyze viral vectors and nucleic acids.