BioXtreme deXtreme - Innovative Post-Stroke Rehabilitative Device
Based on real-life adaptive processes, BioXtreme has developed a robotic arm coupled with adaptive algorithms for the treatment of upper limb post-stroke rehabilitation. Utilizing a 3D VR environment to motivate patients, the deXtreme™ device delivers unparalleled results in the field of neurorehabilitation.
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Product Details
Revolutionizing Rehabilitation Robotics Stroke Neurotherapy
100% additional improvement of motor recovery for stroke patients
BioXtreme is instilling new dexterity for stroke patients. Using groundbreaking error enhancement technology, we significantly shorten recovery time.
Revolutionizing Neurorehabilitation for Stroke Patients
The BioXtreme solution uses the body’s natural physical adaptive reactions without the need to rely on cognition,during our completely reimagined therapy sessions. Our methodology shortens recovery time from stroke for upper limbs and dramatically improves position accuracy and stability while increasing range of motion (compared to other therapy methods).
How Does It Work
Adaptive Learning
Our method is based on the body’s reaction to changes in environmental forces
Error Enhancement
A robotic system applies error enhancement forces during motor practice
Instinctive Correction
The forces applied trigger the patient to the immediate instinctive correction of movement
Introducing New Approach to Motor Learning
Our innovation lies in the combination of a new approach to motor learning and groundbreaking technology. A unique robotic device applies motor error enhancement forces that operate during practice in a virtual environment. The forces stimulate the body’s instinctive adaptive response, which does not require the use of cognition to correct the movement.
The setting of stroke patients in a simulated environment enhances patient motivation and participation. The completion of “games” (tasks) is a great indicator for the patients that they are progressing in the treatment and are on their way to recovery.
The system does not rely in any way on guidance – manual or robotic. Rather, the error enhancement forces lead the patient to perform the correct movement.
Our physical therapy treatments for upper limb stroke patients improve position accuracy and stability while increasing range of motion. In fact, therapy time is shortened by up to 50%, compared to traditional therapies and other technologies. Patients using deXtreme demonstrate 100% improvement in motor results compared to other patients.
Motor Improvement by Error Enhancement Forces - How Does It Work?
Our post-stroke rehabilitation methodology was inspired by two key findings:
- The brain predicts forces that are necessary for an upcoming movement and programs muscle activation accordingly
- When force prediction is incorrect, movement errors drive adaption of the motor commands
The adaptive instinct that occurs for changes in environmental forces is called “After Effect”, representing the change that has been made in movement patterns. We’ve harnessed this adaptive instinctive force response to create our unique movement error therapy:
- The patient performs a movement with an error; the system is measuring the movement.
- The system applies an error-enhancing force.
- Adaptive instinctive force response by the patient corrects the enhanced error by the system.
- The system removes the applied force, resulting in error-free movement performed by the patient.
How Does It Work
Unique robotic system applies motor error enhancement forces in a combined virtual environment to restore and rehabilitate motion and dexterity. The enhanced error forces stimulate an adaptive corrective response from the patient, which leads to the regulation of the system until the desired trajectory is accomplished by the patient.
The process shortens upper limb therapy time by up to 50% and patients achieve 100% additional motor improvement compared to traditional physical therapy methods.
Validation & Results
Three clinical trials have been completed in Israel and delivered the following results:
- Neurorehabilitation time for stroke patients shortened by up to 50%
- Motor results improved by up to 100% (compared to patients using other technologies)
Two additional clinical trials are currently on-going in Leuven, Belgium and Tel-Aviv, Israel, for a total of 80 patients.
deXtreme™ 3.1 has completed development stages and is market-ready. The device is FDA and CE registered.
BioXtreme singular methodology and technology are globally patent protected.
Singular Rehabilitative Technology for Upper Limb Therapy
The Therapy Environment
- Virtual environment based application in 3 dimensions to create fully-cutomized movement exercising scenes
- User-friendly interface for patient and therapist
The Rehabilitation Robot
- Robotic arm engaged to the upper limb equipped with various sensors to measure movement performances
- Motors to enable controlled movements and error enforcement and enhancement in 3 dimensions
The Algorithms
- Error enhancement algorithms
The Control and Monitoring System
- Realtime control system for commanding the motors, based on calculated measured data and the error enhancement algorithm outcomes
- Therapy programming and results presentation
deXtreme™ System Ensures Seamless and Impactful Treatment Sessions
Device Interface
- Quick and convenient transition between the system seat and wheelchair
- Minimal transition between right-side and left-side practices
- Convenient grip of the robot arm and patient’s palm
- Enhanced access for more-limited patients, such as anti-gravitational forces and armrest
- Robotic system is easily movable between treatment rooms
Dynamic and Responsive Post-Stroke Rehabilitation
- Automatic adjustment of treatment and therapeutic parameters
- Automatic adjustment of patient practice ranges based on patient ability and dimensions
- Immediate feedback on success and progress, for patient and therapist alike
- Game-based therapy practices to engage patients and increase motivation
Technology
- Achieving Patient Recovery
- Through Adaptive Post
- Stroke Rehabilitation
New Therapeutic Method Based on Innovative Error Enhancement Technology
- Robotic-based rehabilitation physical therapy for upper limb stroke patients.
- deXtreme utilizes adaptive instinctive corrective force responses to shorten recovery time.
- We let go of the reliance on cognition and harness the body’s ability to adapt to changes in environmental forces in order to shorten recovery time from stroke and other neurological injuries.
Introducing New Approach to Motor Learning
Our innovation lies in the combination of a new approach to motor learning and groundbreaking technology. A unique robotic device applies motor error enhancement forces that operate during practice in a virtual environment. The forces stimulate the body’s instinctive adaptive response, which does not require the use of cognition to correct the movement.
The setting of stroke patients in a simulated environment enhances patient motivation and participation. The completion of “games” (tasks) is a great indicator for the patients that they are progressing in the treatment and are on their way to recovery.
The system does not rely in any way on guidance – manual or robotic. Rather, the error enhancement forces lead the patient to perform the correct movement.
Our physical therapy treatments for upper limb stroke patients improve position accuracy and stability while increasing range of motion. In fact, therapy time is shortened by up to 50%, compared to traditional therapies and other technologies. Patients using deXtreme demonstrate 100% improvement in motor results compared to other patients.
Motor Improvement by Error Enhancement Forces - How Does It Work?
Our post-stroke rehabilitation methodology was inspired by two key findings:
- The brain predicts forces that are necessary for an upcoming movement and programs muscle activation accordingly
- When force prediction is incorrect, movement errors drive adaption of the motor commands
The adaptive instinct that occurs for changes in environmental forces is called “After Effect”, representing the change that has been made in movement patterns. We’ve harnessed this adaptive instinctive force response to create our unique movement error therapy:
- The patient performs a movement with an error; the system is measuring the movement.
- The system applies an error-enhancing force.
- Adaptive instinctive force response by the patient corrects the enhanced error by the system.
- The system removes the applied force, resulting in error-free movement performed by the patient.
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