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Cfm Medical Equipment & Supplies In Netherlands Antilles
5 equipment items found
Manufactured by:Cfm Oskar Tropitzsch GmbH based inMarktredwitz, GERMANY
17-DMAP-GA belongs to the Geldanamycin family. It is an HSP90 inhibitor. 17-DMAP-GA was shown to be a powerful inhibitor of cancer cell growth (IC50 below 100 nm). Its binding affinity to HSP90 was not significantly affected compated to Geldanamycin and other analogs while its water solubility was highly improved compated to 17-AAG. Reference: ZQ Tian et al. Bioorg. Med. Chem 2004 ...
Manufactured by:Cfm Oskar Tropitzsch GmbH based inMarktredwitz, GERMANY
Agelenin has been isolated from the venom of the Agelenidae spider Agelena opulenta. This toxin suppresses the excitatory postsynaptic potentials possibly by blocking the presynaptic calcium ...
Manufactured by:Cfm Oskar Tropitzsch GmbH based inMarktredwitz, GERMANY
Alpha-conotoxin GI act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This conotoxin has been isolated from the venom of the cone snail Conus geographus. The higher affinity site for alpha-conotoxin GI is the alpha/delta site on mouse muscle-deriverd BC3H-1 receptor, and the other site (alpha/gamma site) on nicotinic receptors from ...
Manufactured by:Cfm Oskar Tropitzsch GmbH based inMarktredwitz, GERMANY
17-AEP-GA belongs to the Geldanamycin family. It is an HSP90 inhibitor. 17-AEP-GA was shown to be a powerful inhibitor of cancer cell growth (IC50 below 100 nm). Its binding affinity to HSP90 was not significantly affected compated to Geldanamycin and other analogs while its water solubility was highly improved compated to 17-AAG. Reference: ZQ Tian et al. Bioorg. Med. Chem 2004 ...
Manufactured by:Cfm Oskar Tropitzsch GmbH based inMarktredwitz, GERMANY
17-AH-Geldanamycin is a semi-synthetic analog of geldanamycin containing a linker bearing a free NH2 functional group for conjugation. Selectively binds to HSP90. 17-AH-Geldanamycin has been used in a copolymeric composition for sustained delivery and controlled release (1,2) as well as other applications. References: 1. MP Borgman et al. Mol. Pharm. 2009 6:1836; 2. Y Kasua et al. J. Control. ...