CELLINK - Model LUMEN X - DLP Bioprinter
From CELLINK - Bioprinters - Light-based
The Lumen X, powered by Volumetric, leverages digital light processing (DLP) printing to offer users high resolution, high throughput and high fidelity, enhancing applications in microfluidics, cell-laden hydrogels, macroporous structures and more. Designed to bioprint vasculature with visible blue light (405 nm), the Lumen X gives you a powerful advantage in achieving complex branching and tapering of vessels. Lumen X is being launched through an exciting partnership with CELLINK and Volumetric, a Texas-based startup. We have combined our expertise to optimize the technology for all your bioprinting needs.
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Description
The Printing Principle
The Lumen X builds solid hydrogels by beginning with a droplet of light-sensitive, liquid PhotoInk™ in a vat. An industrial blue-light projector exposes a series of images onto the vat, like a slideshow. The areas of the droplet that are exposed will crosslink and solidify into a single layer. The build platform moves up to allow each layer to stack and build the part.
Features
Biocompatibility
Lumen X PhotoInks are biocompatible, so cells can be used with printed constructs. When using GelMA, cells can even be mixed into the PhotoInk. The built-in heater keeps GelMA liquefied and improves cell viabilitywithin the PhotoInk.
Flexibility
Combining the Lumen X with CELLINK’s BIO X™ lets users multiply the benefits of each system’s state-of-the-art capabilities. For example, the BIO X can print living cells within a structure fabricated on the Lumen X to strengthen work in applications like multimaterial research.
Isotropy
Compared to extruded scaffolds, Lumen X scaffolds are significantly more isotropic, allowing users to control mechanical properties with geometry in all dimensions. Users can also build unique structures, such as Schwarz lattices or auxetic structures.
Resolution
DLP technology coupled with Volumetric PhotoInks allow the Lumen X to build watertight channels in hydrogels with greater consistency and precision than extrusion. This allows the Lumen X to create microfluidic lab-on-a-chip devices, strengthening work in:
- Disease pathology
- Drug screening
- Tissue engineering
- And more!
Open Materials Platform
The Lumen X allows users to develop and use their own materials without workarounds or extra fees, opening the door for the development of materials with unique properties or for novel tissue engineering applications.
Speed
By curing entire layers simultaneously, the Lumen X can build structures 10 mm tall in GelMA in 30 minutes (up to 50 times faster than other printing methods). This translates to better cell viability and higher throughput when model building.
Clarity
The photo-absorbing dye that gives the PhotoInks their color will wash out of printed structures in a matter of hours, allowing structures to be imaged via bright-field or fluorescence imaging techniques.
Intricacy
Gentle separation forces and material strength allow the Lumen X to build intricate scaffold geometries that include porosity and vasculature in X, Y and Z dimensions. Scaffolds can now have geometry that is far more biomimetic when engineering tissue such as trabecular bone.
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