Clinical dynamics
Metabolism in critical care
Controlling glucose in critical care settings is medically essential, sustaining the body`s ability to defend against acute complications and effectively heal. This is a vital factor for 80% of critical care patients, regardless any prior diagnosis of diabetes. Similarly, early detection of sepsis, for which lactate is a key diagnostic indicator, is pivotal to survivability. The combined impact of these is substantial:

Metabolic parameters such as glucose and lactate can change rapidly in critical care patients. Seeing variability accurately in real time is crucial. This requires:

Sufficiently high frequency of measurement; and Measurement in blood, since interstitial fluid is unreliable under pathophysiologies of critical care (edema, fluctuations in interstitial volume, temperature, and oxygen concentration).
This combination is precarious, since frequent blood draws often lead to hospital-acquired anemia, which requires transfusion.

Workflow and efficiency
To date, the standard of care for blood chemistry analysis and glucose control has been entirely manual. The clinical team draws blood, measures its chemistry using a lab analyzer or handheld instrument, calculates an insulin dose, and adjusts an infusion pump to administer the therapy. The clinical burden of this is significant and occurs in the context of shortages in skilled clinical personnel and escalating demand:

7 min/hr occupying 2 nurses
42% shortage in nurse staffing projected by 2030

This process limits the standard of care, the number of patients who may be cared for, or both.

Previously unachievable precision
Everything thus far has been a compromise out of necessity. High-precision automation changes this equation.

Admetsys PrecisionOne -Clinical Automation Controller