Cortiva - Allograft Dermis
From RTI - Surgical Implants Portfolio - Plastic & Reconstructive Surgery
Cortiva Allograft Dermis is a non-crosslinked acellular dermal matrix offering a safe and natural biologic option and sterilized to a sterility assurance level (SAL) of 10-6 through the Tutoplast® Tissue Sterilization Process.
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Overview & Features
Implants
- Cortiva® Allograft Dermis
- Cortiva® 1mm Allograft Dermis
- Cortiva® 1mm Tailored Allograft Dermis
Safety
- Sterilized through the Tutoplast Process
- Graft labeled sterile
- Validated viral inactivation
Performance
- Fast rehydration – 30 seconds on average1
- High mechanical strength 2,3*
- Equivalent revascularization4**
- Rapid cellular repopulation4,5,6**
Handling Properties
- Five-year, room-temperature shelf life — no refrigeration required
1Data on file – Rehydration study comparing Cortiva to Standard Tutoplast Sterilized Dermis 2013.
2Data on file – Doc #7042. Benchtop Testing comparing Cortiva to Standard Tutoplast Sterilized Dermis 2013.
3Hollinsky C, Sandberg S. Measurement of the tensile strength of the ventral abdominal wall in comparison with scar tissue. Clinical Biomechanics. 22 (2007) 88 – 92.
4Data on file – 4 & 8 week rat model comparing Cortiva1mm to Standard1mm Tutoplast Sterilized Dermis 2012.5.
5Deeken CR, Melman L, Jenkins ED, et al. Histologic and biomechanical evaluation of crosslinked and non-crosslinked biologic meshes in a porcine model of ventral incisional hernia repair. J Am Coll Surg. 2011 May; 212(5):880-8.
6Novitsky YW, Rosen MJ. The biology of Biologics: Basic Science and Clinical Concepts. Plast Reconstr Surg. 2012 Nov;130(5 Suppl 2): 9S-17S.
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