diasorin - SARS-CoV-2 Diagnostic Solutions
DiaSorin strives to improve health-care around the globe through the development of innovative diagnostic solutions that can lead to better patient outcomes and provide economic benefits to the healthcare system. Thanks to its team of dedicated scientists DiaSorin has been able to promptly deliver diagnostic solutions to manage the COVID-19 pandemic emergency.
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DiaSorin provides diagnostic laboratories with solutions that include detection of SARS-CoV-2 Ag, antibodies determination and molecular testing:
- LIAISON® SARS-CoV-2 Ag
- LIAISON® SARS-CoV-2 IgM
- LIAISON® SARS-CoV-2 TrimericS IgG (New!)
- LIAISON® SARS-CoV-2 S1/S2 IgG
Simplexa™ COVID-19 Direct Kit - For more info visit DiaSorin Molecular
A High-Quality Tool to Verify Immune Responses of Vaccinated Individuals
DiaSorin is supporting Public Health Systems confirm the efficacy of their vaccination strategy with a cost-effective, automated, high-throughput SARS-CoV-2 serology testing solution.
- The LIAISON® SARS-CoV-2 TrimericS IgG assay enables the reliable detection of Trimeric S spike protein IgG antibodies – the body’s natural defense response against SARS-CoV-2.
- The LIAISON® SARS-CoV-2 TrimericS IgG assay is able to identify patients diagnosed for COVID-19 by virus variants (Lineage B.1.1.7 and Lineage P.1)
- The solution was used to evaluate pre- and post-vaccination samples to support the Italian national vaccine program at a hospital in Alessandria (Italy)
- A total of 102 sets of samples were collected from apparently healthy adults that were SARS-CoV-2 IgG negative at the time of vaccine and who received the full course (2 injections) of the Pfizer vaccine, COMIRNATY®
- The LIAISON® SARS-CoV-2 TrimericS IgG was able to verify the effectiveness of the vaccine with a sensitivity of 99% (21 days after the first injection) and 100% (21 days after the second injection).
A Quantitative Assay for Immune Status Monitoring With an Accurate Correlation of Neutralizing Igg Antibodies
The LIAISON® SARS-CoV-2 TrimericS IgG assay is the second generation of DiaSorin serological tests with an important diagnostics improvement. The selection of a new recombinant Trimeric Spike glycoprotein as a capture antigen, offers a new product with high standard quality that provides the following benefits:
- A quantitative assay for the detection of IgG antibodies anti-Trimeric Spike glycoprotein of SARS-CoV-2
- Trimeric Spike Glycoprotein is the stabilized native form of the SARS-CoV-2 Spike protein and a stabilized trimer may elicit an accurate detection of IgG Neutralizing antibodies
- Clinical Sensitivity: 98.7% - Clinical Specificity: 99.5%
- Correlation with Microneutralization test: PPA: 100%, NPA: 96.9%
- A fully automated solution with up to 171 results/hour on LIAISON® XL
- Complete traceability combined with a simplified sample workflow
The Selection of the Antigen for the Assay: The Value of Using Sars-Cov-2 Recombinant Trimeric S Glycoprotein.
- Trimeric Spike Glycoprotein is a stabilized trimer offering an improved detection of IgG Neutralizing antibodies.
- For diagnostics, the Trimeric Spike Glycoprotein detects a broader repertoire of Neutralizing Antibodies improving sensitivity and accuracy of the immune status monitoring.
- Trimeric Spike Glycoprotein improved the sensitivity and the specificity with a better correlation with the Microneutralization test.
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