Evaxion EDEN - Second AI Platform - Prophylactic Vaccine
EDEN is our second AI platform that rapidly identifies novel, highly protective antigens for the use in pathogen-specific prophylactic vaccines against bacteria. EDEN has been designed to rapidly identify those antigens that will trigger a robust protective immune response against almost any bacterial infectious disease. In addition, EDEN redesigns identified antigens to optimize their antigenic and structural properties as well prepare them for production, which allow us to move antigen candidates into the clinic far faster than traditional, vaccine discovery approaches.
Details
EDEN has been pre-clinically validated in seven different pathogens in mouse infection models, and we believe our approach can be used to target almost any bacterial infection and rapidly enables the discovery and development of vaccine candidates.
Advantages:
- Highly Efficient and Reduced Attrition: Predicts protective vaccine antigens with great precision
- Identification of Novel and Unbiased Targets: Identifies underlying feature patterns enabling discovery of novel vaccine targets
- Data Driven Precision: AI-based identification of novel targets and filters irrelevant proteins reducing burden on pre-clinical development
- Ability to Provide Broad Protection: Leverages genomic sequencing data to identify targets or domains present in clinical strains
- Optimizes Antigen Design: AI models optimize antigenic and structural properties and allows for ease of production
- Speed: Completes antigen discovery in as little as 48 hours and identifies vaccine candidates in weeks
- Scalability: Can be applied in the discovery of vaccine candidates in almost any bacterial infectious disease
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