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Model Anti-Insulin -ELISA-Based, Automated, In-Vitro Test System
Anti-Insulin is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against animal (beef, pork) and human insulin in human serum or plasma. Anti-Insulin is an ELISA test for the quantitative determination of IgG antibodies against human, bovine and pig insulin in human serum or plasma. Type I diabetes mellitus is an autoimmune disease triggered by autoantibodies against pancreatic islet cells and against insulin itself. Autoantibodies against insulin can appear in the prediabetic phase of type I diabetes mellitus or once the condition manifests.
These autoantibodies are found in 50 to 70 % of children with diabetes mellitus and 20 to 30 % of affected adults. In rare cases, insulin-dependent diabetes patients generate antibodies against exogenous insulin. These antibodies can give rise to insulin-resistance and should therefore be controlled regularly when monitoring insulin therapy. The wells of the Anti-Insulin ELISA from ORGENTEC are coated with a mixture of bovine, pig, and recombinant human insulin.
- Product Number: ORG 220
- Tests: 24 Alegria® strips
- Calibration: internal
- Calculation: quantitative
- Range: 0 - 100 U/ml
- Cut-off: 10 U/ml
- Coating: insulin (bovine, porcine, human recombinant)