ALA - Model III - FiberOptoMeter

The new FiberOptoMeter III:

• In-vivo Ca2+ fluorescence measurement through optical fiber
• Improved design using new detectors with superior capabilities
• Optional output signal filter improves signal to noise ratio
• Available with multiple fibers

The applications are:

• Localized measurement of physiological fluorescence signals (e.g. Ca²⁺ signals) from multiple sites in stimulation of physiological signals in disease model animals and drug testing freely behaving animals including primates
• Multi-color stimulation
• Near simultaneous optical measurement of cellular activity and stimulation
• Chronic monitoring of physiological signals in disease model animals and drug testing

• Dual-band excitation:
  450 – 490 nm (OGB1, GCamP, ChR2)
  550 – 590 nm (ArchT)
  Fluorescence recording in 500 – 540 nm band
  Other wavelengths available. Please contact us for further details.
• short pulses at high power (optogenetics) on top of
• constant low power illumination (fluorescence)
• Ultrafast photodetector:
  high robustness against high-dose irradiation detecting fluorescence signal immediately after optogenetic stimulation with high sensitivity
• can also be used as supplemental photodetector channel for multiphoton microscopy
• compatible with multi-mode SMA or FC/PC fibers incl. non magnetic fibers for fMRI

vailable central wavelengths (LED):

450 nm, 470 nm, 570 nm, 617 nm, 625 nm

Other wavelengths available. Please contact us.

Excitation band:

450 – 490 nm (blue)

540 – 590 nm (orange)

Other wavelengths available. Please contact us.

Max. light power at 200 µm fiber tip (determined with module):

110 mW/mm² (blue)

65 mW/mm² (orange)

Fiber interface:

SMA or FC/PC

Fluorescence detection band:

500 – 540 nm (green)

Fluorescence signal output filter:

340 Hz low-pass

Fluorescence signal output range:

0 ~ -3 V (negative polarity)

Dimensions:

(W x D x H) 365 mm x 260 mm x 130 mm

Power consumption:

20W

We offer the FiberOptoMeter III in various different configurations:

• 1 LED, 1 detector
• 2 LED, 1 detector
• 1 LED, 2 detectors
• 2 LED, 2 detectors

We customize every FiberOptoMeter III to fit exactly to the fluorophors you are using. Since there is a large variety of filters, dichroics and LEDs available, please contact us for further information or pricing.