Vobis - Films
Our films are about the size of a postage stamp and can deliver therapeutic actives through the oral mucosal tissue, sublingually or buccally – between the cheek and gum – or more traditionally via the gastrointestinal tract. Oral transmucosal drug delivery is a non-invasive route reserved for pharmaceutical drugs that allows for absorption directly into the vascularized tissue in the mouth, bypassing the hepatic first pass effect. This leads to reduced drug exposure and can offer a rapid onset of action.
- Multiple actives up to 200 mg
- Stable at room temperature for most active ingredients
- Ease of use - melt in your mouth; no need for water, swallowing or chewing
- Immediate - buccal absorption - absorbed directly into tissue in the mouth and into the bloodstream
- Fast acting - potential for faster onset, clinical effect and symptom relief
- Deliver actives through the oral mucosal tissue either sublingually or buccally
- Noninvasive
- Actives can be encapsulated or pre-solubilized within the film matrix
- High load: direct multiple actives that are stable at room temperature
- Precision dosing: uniform distribution allows for precision dosing
- Decreased risk: potential for reduced side effects with a lower dose
- Suitable for both pharmaceuticals and wellness products (per oral only)
Active ingredients in the film dose form can be either pre-solubilized within its matrix or encapsulated, or both for more effective absorption and/or sustained release. As oral thin films quickly dissolve, no water is required for their administration, improving patient compliance – especially among the elderly, children, and in conditions where patients have difficulty in swallowing.