FluidFM - Hollow Force Sensitive Probe Technology
From Technology
FluidFM technology unites the best features of microfluidics and force microscopy. Our proprietary FluidFM (Fluidic Force Microscopy) technology uses closed microscopic channels in force sensitive probes. These probes have apertures down to 300 nm and allow to simultaneously sense interaction forces down to pN and to dispense or aspirate femtoliter volumes. This truly unique combination enables novel experimental designs for a wide range of applications in life sciences, biophysics and mechanobiology.
-
Most popular related searches
Product Details
Microfluidic channel
Enables the handling of femtoliter volumes. Soluble molecules can be dispensed or aspirated through a sub-micrometer aperture at the tip of the probe.
Sensitive force-feedback
Provides a reliable distinction between gentle contact with cell membranes and perforation. Surfaces in liquid environments can be modified in a controlled fashion.
- Femtoliter: Control fL liquid volumes
- Precise pressure control: With 0.1 mBar resolution
- Any viscosity: From 1 to 10'000 cP
FluidFM modes - for a variety of applications
Our hollow FluidFM Probes exist in a variety of tip shapes, aperture sizes and mechanical specifications, specifically designed to enable three basic modes. With those three modes and the combinations thereof, innovative new applications in neuroscience, virology, mechanobiology or cell line development become possible.
Pick & Place
Grab and relocate single cells and other micro-sized objects.
Injection & Sampling
Inject into and extract from single cells. Volume quantification possible.
Dispensing & Nanoprinting
Dispense the tiniest amount of liquid. In air or in immersion.
FluidFM Probes - different types optimized for your needs
The FluidFM Micropipette exists with 2, 4 and 8 µm apertures, ideal to reversibly immobilize individual cells and objects of different sizes.
Ideal for:
- Pick & Place
- Dispensing & Nanoprinting
The sharp apex of the FluidFM Nanosyringe enables gentle probe insertion into a cell. Inject into or extract from the cytoplasm or nucleus.
Ideal for:
-
Injection & Sampling
The FluidFM Nanopipette has with 300 nm the smallest aperture in our standard probes range. It is ideal for localized dispensing of liquids.
Ideal for:
- Pick & Place
- Dispensing & Nanoprinting
Ready to use
The FluidFM chip, integrating the microfluidics and the hollow cantilever with its specific tip and aperture, comes pre-glued on a convenient adapter tailored to your system. Therefore, FluidFM Probes are ready to be filled and used for your experiment.
FluidFM Probe zoom in: Every FluidFM Probe consists of a polymer adapter, tailored to the specific system, and a FluidFM chip that integrates the microfluidics as well as the hollow cantilever with a specific tip and aperture (last image).
Get started within minutes
Pipette the desired solution into the reservoir of the FluidFM Probe, connect the probe to your system, fill the microchannel by applying a small positive pressure and the system is ready to be used.
Get started within minutes
Pipette the desired solution into the reservoir of the FluidFM Probe, connect the probe to your system, fill the microchannel by applying a small positive pressure and the system is ready to be used.
Know how your probe looks like
FluidFM Probes are pre-assembled and individually wrapped in a tailor-made hermetically sealed blister package. The QR-code printed on the package gives convenient access to all relevant probe characteristics, most importantly to a unique SEM image of each individual FluidFM Probe taken during our quality control process. You can see exactly how your probe opening looks like.
Customer reviews
No reviews were found for FluidFM - Hollow Force Sensitive Probe Technology. Be the first to review!