C.STATION -Fully Automated Stable Cell Line Development
Optimize and streamline entire cell line development (CLD) workflows with this automated, intuitively designed workstation. From single-cell cloning of transfected cells to selecting high-producing clones to upscaling, the all-new C.STATION fully automates stable CLD for monoclonal antibody production.
Confluency, cell count and viability of clonal cells are effortlessly monitored by the UP.SIGHT. The C.STUDIO software lets you track growing colonies over the course of an experiment while the instrument enables you to rewind and replay images, providing a full picture of the CLD workflow. With the confluency tool, determine the right timepoint to pick clones for a larger volume plate format.
The C.STATION comes with built-in titer quantification based on a plate-based assay. This makes it possible to screen hundreds of clones without user interaction. With the C.STUDIO, clone selection based on relative productivity is straight forward and guarantees data traceability.
The C.STATION integrates CYTENA’s flagship instrument, the UP.SIGHT, to enable a probability of clonality >99.99% and fulfill required regulatory expectations. Double assurance of clonality is achieved through nozzle images and 3D Full Well Imaging, a new and innovative method that images the full volume of each well from the point of dispensing using the integrated imager. First, images are taken at the dispensing nozzle to ensure only one cell is placed in each well and nonclonal droplets are discarded. Then, the single cells are confirmed once more with 3D Full Well Imaging.