GammaTile Therapy - Surgically Targeted Radiation Therapy (STaRT)
GammaTile Therapy is a Surgically Targeted Radiation Therapy (STaRT) that provides immediate, dose-intense treatment at the completion of resection. By getting a head STaRT on fighting the tumor, resection plus GammaTile Therapy can extend local recurrence-free survival with minimal complications, reduced patient burden, and assured compliance.
Details
GammaTile Therapy vs Intensity-Modulated Radiation Therapy (IMRT)
GammaTile is designed with uniform radiation-source spacing to ensure an even dose distribution. The favorable depth-dose profile optimizes local tumor control.[2]
The colors indicate the radiation location and int...
The colors indicate the radiation location and intensity from the 2 types of treatment. Blue-green indicates lower radiation levels. Red indicates higher levels. The extracranial dose is likely lower than shown, as the planning system did not utilize inhomogeneity corrections.
How It Works.
GammaTile Therapy targets tumor cells while preserving brain tissue. Surgically guided treatment of the local radiation dose to the operative bed optimizes the therapeutic margin while minimizing complications.[1]
Structural offset of the radiation source from the brain tissue prevents harmful direct seed-to-tissue contact and enables intraoperative adjustment.
- 50% of the therapeutic dose is delivered within the first 10 days after surgery, which helps prevent residual tumor cells from replicating.[11]
- 88% of the therapeutic dose is delivered within 30 days, with more than 95% of the dose delivered by 6 weeks.[11]
- A favorable depth-dose profile optimizes local tumor control.[2]
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