Invivo -Gel

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First, INVIVO GEL provides a degree of freedom to tune the elastic modulus (or stiffness) according to user’s specific needs by changing concentration of INVIVO GEL (GELMA) and Gel-linker (A), a photo initiator. Also, by changing UV light (365㎚) exposure time, degree of cross-linking can be adjusted.  Second, special INVIVO GEL formulation mimics extracellular environment and excellent growth factor (VEGF A, TGF-β1, BMP-2, or GF of your choice) retention capability allows precise control of the extracelluar environment to the specific needs of your research.

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MATERIALS: INVIVO-GEL (GeLMA)
CONDITION
  • Seeding density: 6 x 105 cells/? (ADSC)
  • UV exposure time: 45sec
  • Scale bar – 500um
  • ADSC viability test

* ADSC: adipose derived stem cells

INVIVO-GEL
MATERIALS: INVIVO-GEL (GeLMA)
CONDITION
  • Seeding density: 5 x 105 cells/? (ADSC), 1 x 105 cells/? (RFP-HUVEC)
  • UV exposure time: 45sec
  • Scale bar – 100um
  • Vascularization test

* HUVEC: Human Umbilical Cord Vascular Endothelial Cell

The INVIVO-GEL kit is specifically developed and optimized for bioprinting of 3D structures. The INVIVO-GEL Essential kit includes optimally formulated gelatin-based hydrogel complex contained in syringes for easy dispensing. The kit also includes Gel-linker(A) (photoinitiator), which reinforces mechanical stability and Gel-linker (B) (Growth factor) which helps to induce cells to adjust proliferation or differentiate into a specific phenotype . A transparent hydrogel forms when contents are properly mixed and exposed to UV light.