Episkin -Model T-Skin -Human Full Thickness
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T-Skin is an in vitro reconstructed skin which consists of a dermal equivalent with human fibroblasts overlaid by a stratified, well differentiated epidermis derived from normal human keratinocytes cultured on an inert polycarbonate filter. This model exists at different stages of maturity.
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Specific markers
Differentiation markers:
- Filaggrin (See picture)
- Involucrin
- Loricrin
- Cytokeratin 10 (See picture)
- Transglutaminase-1 (See picture)
Dermal-Epidermal junction markers
- Collagen IV, VII, XII (See picture)
- Laminin V (See picture)
- Perlecan (See picture)
- BP antigen
Proliferation markers
- Ki67 (See picture)