InSphero 3D InSight -Human Islet Microtissues Uniform
3D InSight™ Human Islet Microtissues are a standardized alternative to primary human pancreatic islets for reproducible, reliable, and more efficient research. Expand your GSIS assay window and improve sensitivity to insulin secretagogues with a long-lived, robust model persisting more than 28 days in culture. Eliminate islet pooling and data normalization with islet microtissues homogeneous in size and cellular composition. Increase efficiency 6-fold by eliminating the need to hand pick islets with microtissues available bimonthly and delivered assay-ready in a non-adherent, 96-well plate.
Production of 3D InSight™ Islet Microtissues starts with fine-tuned dissociation of primary donor islets, followed by controlled scaffold-free cellular reassembly and maturation in customized media that support maximum survival and optimal metabolic functionality of highly sensitive primary islet cells. The resulting uniform islets provide minimal intra-assay and intra-donor variability, while sustaining robust and long-term function.
