Genmab A/S

Genmab OfatumumabHuman Monoclonal Antibody

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Ofatumumab is a human monoclonal antibody which targets an epitope in the CD20 molecule encompassing parts of the small and large extracellular loops.

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Indication and Safety

Ofatumumab is approved in the U.S. as Kesimpta® for the treatment of relapsing multiple sclerosis (RMS) in adults, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. It is the first B-cell therapy that can be self-administered at home by patients using a Sensoready® autoinjector pen.