Aortic dissection is complex and difficult to treat.^4,5Hemiarch repair alone isn’t enough to stop a dissection from causing significant complications^4-7including:

High Mortality^5,8+ Re-intervention^6,8
Aortic Growth^6,9
Malperfusion^{4,6 x}

Consider the Implications of Distal Anastomotic New Entry (DANE) following a Standard Repair for Acute TAAD

Distal anastomotic new entry (DANE) in the standard hemiarch repair for TAAD is considered to be one of the causes of patent false lumen (PFL) after acute type I aortic dissection repair.^9-12 DANE is observed in 40-70% of patients post hemiarch repair.^6,10

An Untreated DANE Can Lead to:

High Mortality

Survival with a patent false lumen gets significantly worse over the years, with a reduced actuarial survival by over 10% at 5 years and over 30% at 10 years compared to patients with occluded false lumen.¹¹

Aortic Growth

A patent false lumen with DANE is associated with significantly greater aortic growth compared not only to a thrombosed false lumen, but also patent false lumen without DANE.⁹

Malperfusion

Between 30-55% of all acute TAAD patients present with malperfusion.^4,13,14In-hospital mortality rate can be 5X higher in patients presenting with any malperfusion vs. patients presenting without malperfusion.¹³ At least 25% of patients have post-operative malperfusion syndrome.⁴

Artivion - Model AMDS - Hybrid Prosthesis

Products Details