
Taconic -Model B6JBom -Inbred Mouse Model
The Black 6 Bom inbred model was developed by Little et al. Hall received stock. Jackson Laboratory received stock from Hall in 1948. Zentralinstitut für Versuchsteirzucht, Hannover Germany (Han) received stock in 1971. M&B A/S (now Taconic Europe) received stock at F141 in 1988. The mice were derived by embryo transfer in January 2000. The Taconic US foundation colony was at F156 + 35 in 2005.
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- Slightly smaller than the C57BL/6NTac, this subline is extensively used in the research applications of oncology, immunology, and toxicology
Genetics:
- Strain Profile: Akp1a, Akp2b, Anpepa, Car2a, Es1a, Es2b, Es3a, Es5b, Es9a, H6pd1a, Gpi1b, Got2b, Hbbs, Idh1a, Ldr1a, Ldr2a, Mod1b, Mup1b, Pep3a, Pgm1a, Trfb
- Immunology: H2b
- The C57BL/6JBomTac substrain carries a mutation in the Y chromosome. More information is available in the following two papers: MacBride MM et al. Mild reproductive impact of a Y chromosome deletion on a C57BL/6J substrain. Mamm Genome 2017; 28(5-6):155-165 and Fischer M et al. Large deletion on the Y-chromosome long arm (Yq) of C57BL/6JBomTac inbred mice. Mamm Genome 2017; 28(1-2):31-37.
Coat Color Loci:a
Color:Black
Species:Mouse
Animal Diet:NIH #31M Rodent Diet