Taconic -Model B6JBom -Inbred Mouse Model

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The Black 6 Bom inbred model was developed by Little et al. Hall received stock. Jackson Laboratory received stock from Hall in 1948. Zentralinstitut für Versuchsteirzucht, Hannover Germany (Han) received stock in 1971. M&B A/S (now Taconic Europe) received stock at F141 in 1988. The mice were derived by embryo transfer in January 2000. The Taconic US foundation colony was at F156 + 35 in 2005.

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  • Slightly smaller than the C57BL/6NTac, this subline is extensively used in the research applications of oncology, immunology, and toxicology
Genetic Background:C57BL/6JBomTac Background

Genetics:
  • Strain Profile: Akp1a, Akp2b, Anpepa, Car2a, Es1a, Es2b, Es3a, Es5b, Es9a, H6pd1a, Gpi1b, Got2b, Hbbs, Idh1a, Ldr1a, Ldr2a, Mod1b, Mup1b, Pep3a, Pgm1a, Trfb
  • Immunology: H2b
  • The C57BL/6JBomTac substrain carries a mutation in the Y chromosome. More information is available in the following two papers: MacBride MM et al. Mild reproductive impact of a Y chromosome deletion on a C57BL/6J substrain. Mamm Genome 2017; 28(5-6):155-165 and Fischer M et al. Large deletion on the Y-chromosome long arm (Yq) of C57BL/6JBomTac inbred mice. Mamm Genome 2017; 28(1-2):31-37.
Coat Color Loci:a

Color:Black

Species:Mouse