Daiichi Sankyo Company Limited

VANFLYTAModel FLT3 - Inhibitor

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VANFLYTA is a FLT3 inhibitor approved in Japan for the treatment of adult patients with acute myeloid leukemia (AML) that is FLT3-ITD mutation positive, including for use in combination with standard cytarabine and anthracycline induction and standard cytarabine consolidation chemotherapy and as maintenance monotherapy for newly diagnosed FLT3-ITD positive AML, based on the results of the QuANTUM-First trial, and as a monotherapy for relapsed/refractory AML that is FLT3-ITD positive, as detected by an approved test, based on the results of the QuANTUM-R trial.

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VANFLYTA is approved in the US in combination with standard cytarabine and anthracycline induction and cytarabine consolidation, and as maintenance monotherapy following consolidation chemotherapy, for the treatment of adult patients with newly diagnosed AML that is FLT3-ITD positive, as detected by an FDA-approved test.