InStar - Model Cebedix & Cebedix-h - Oral Thin Films
Cebedix & Cebidix-h are an Oral Thin Films using our InStripTM technology with CBD (Canabidiol). InStrip technology allows you to use the full potential of the substances contained in Cebedix, in this case CBD. You will achieve the desired effect from a much smaller dose. And a smaller dose means a smaller toll on the organism. The first effects of Cebedix in the form of a thin, mouth-soluble film will be felt by you in just a few seconds. Cebedix will be completely dissolved and the contained substances will be used effectively.
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Product Details
Countless experiments and hours of work have to led to the emergence of a complete new and revolutionized technology that we are rightly proud of. The extensive mucoadhesive property facilitates maximum transfer of the active ingredient to the biological systems, which is attributed to greater bioavailability of physiologically active substances.
With our InStrip™
technology we arc able to work with a wide range of physiologically active substances, the delivery of which we can modify according to the nature of substance and requirements of the partner. 'Flic technology gives the advantage to produce products for both human and veterinary use.
Oromucosal administration
The oral route of administration is widely considered as the most convenient and acceptable route for drug administration. We apply our proprietary InStrip™ technology together with years of know-how to create an innovative product which is applicable in the oral cavity.
Non invasive
application of physiologically active substances and evasion of both first-pass metabolism and degradation though gastric enzymes initiates rapid onset of action arc some of the advantages of InStrip™ technology.
With our technology, the scaling up from development phase to production phase becomes straightforward.
Why InStrip technology overcomes others?
Other advantage includes
accurate dosage, combination of different substances in one film, high level of homogeneity and stability in different conditions, absence of useless additives and no water needed for administration.
Use of different
types of pharmaceutical polymers in InStrip technology provides different release profiles ranging from a few seconds to hours, months and even years, depending on the final application.
We have
experience in production of oromucosal films with proteins and peptides which in general have low bioavailability and are thermo-labile, but are suitable for immunization, vaccination, etc. We have years of experience in processing these substances, which have been verified by in vitro and in vivo studies.
InStrip Advantages
- Mucoadhesivity : Enhanced mucoadhesion with improved film retention time. Enhanced mucoadhesive property affix the film at the site of application for prolonged time period. Thus facilitating maximum release of active substance to the mucosal layer.
- Room temperature : The entire process is carried out at room temperature and is devoid of high temperature treatment, thus minimizing the possibility of in-process thermal degradation.
- Pharmacokinetics : InStrip technology facilitates controlling the pharmacokinetics of active substance by controlling the dissolution of nanofiber layers. With prolonged dissolution time, the release of active substance can be delayed.
- Multi drug : InStrip technology involves deposition of different layers of nanofibers. Thus the final product can be multi layered, each with different active substance.
Features
- Developing product addressing unmet therapeutics needs
- Pursuing high technological barrier product
- Identifying unique repurposing opportunities
- Providing lifecycle management opportunities
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