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Ppar Receptor Equipment & Supplies

12 equipment items found

Elafibranor in PBC

Elafibranor in PBC

Manufactured by:GENFIT   based inLoos, FRANCE
Primary Biliary Cholangitis (PBC) is a chronic disease in which bile ducts in the liver are gradually destroyed.1 The damage to bile ducts can inhibit the liver’s ability to rid the body of toxins, and can lead to cirrhosis. Targeting PPAR receptors may result in a reduction of bile acid synthesis, improved detoxification of bile in the bile duct and ...
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Mentanine® - Natural Formulation Developed To Improve Brain Health, Backed By Pre-Clinical Trials

Mentanine® - Natural Formulation Developed To Improve Brain Health, Backed By Pre-Clinical Trials

Manufactured by:CanaQuest Medical Corp.   based inMississauga, ONTARIO (CANADA)
Mentanine®, supported by (cannabidiol “CBD” + IP formula) – molecules bond and synergistically attach to PPAR receptors allowing the formula to cross the blood-brain barrier (BBB) to target the central nervous system (the brain) with amplified effects and efficacy. CBD by itself did not do this in the pre-clinical trials. ...
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Phytol - Model B2455 - Diterpene Alcohol Commonly Activator

Phytol - Model B2455 - Diterpene Alcohol Commonly Activator

Manufactured by:BioVision, Inc.,   based inMilpitas, CALIFORNIA (USA)
A retinoid X receptors (RXRs) activator. Phytol is a diterpene alcohol commonly used as an aromatic ingredient in many fragrance compounds. Phytol and its metabolites have been reported to activate retinoid X receptors (RXRs) and to promote the activity of (peroxisome proliferator-activated receptor) PPAR/RXR heterodimers. ...
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MedChemExpress - Model Anandamide - 94421-68-8

MedChemExpress - Model Anandamide - 94421-68-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2). Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential anti-fungal and anti-inflammatory activities. Anandamide can be used for the ...
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MedChemExpress - Model Bezafibrate-d6 - 1219802-74-0

MedChemExpress - Model Bezafibrate-d6 - 1219802-74-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Bezafibrate-d6 is the deuterium labeled Bezafibrate. Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic ...
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MedChemExpress - Model RSVA405 - 140405-36-3

MedChemExpress - Model RSVA405 - 140405-36-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
RSVA405 is a potent, orally active activator of AMPK, with an EC50 of 1 μM. RSVA405 facilitates CaMKKβ-dependent activation of AMPK, inhibits mTOR, and promotes autophagy to increase Aβ degradation. RSVA405 has anti-inflammatory effects through the inhibition of STAT3 function. RSVA405 can also be used for the research of ...
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MedChemExpress - Model Seladelpar - 851528-79-5

MedChemExpress - Model Seladelpar - 851528-79-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Seladelpar (MBX-8025) is an orally active, potent and specific PPARδ agonist with an EC50 of 2 nM. Seladelpar shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar can be used for the study of primary biliary ...
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MedChemExpress - Model Anandamide-d8 - 924894-98-4

MedChemExpress - Model Anandamide-d8 - 924894-98-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2). Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential anti-fungal and anti-inflammatory activities. Anandamide can be used for the ...
CONTACT SUPPLIER

MedChemExpress - Model Benzbromarone - 3562-84-3

MedChemExpress - Model Benzbromarone - 3562-84-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Benzbromarone is an orally active anti-gout agent. Benzbromarone has anti-infammatory, anti-oxidative stress and nephroprotective effects. Benzbromarone can be used for the research of hyperuricemia and ...
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MedChemExpress - Model GW 501516 - 317318-70-0

MedChemExpress - Model GW 501516 - 317318-70-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
GW 501516 (GW 1516) is a PPARδ agonist with an EC50 of 1.1 ...
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MedChemExpress - Model Bezafibrate - 41859-67-0

MedChemExpress - Model Bezafibrate - 41859-67-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic ...
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MedChemExpress - Model Bavachinin - 19879-30-2

MedChemExpress - Model Bavachinin - 19879-30-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. ...
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