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Angiogenesis Tumor Equipment & Supplies

38 equipment items found

Model L-0186 - (2S)-Oleyl LPA

Model L-0186 - (2S)-Oleyl LPA

Manufactured by:Echelon Biosciences, Inc (EBI)   based inSalt Lake City, UTAH (USA)
Lysophosphatidic Acid (LPA) is a small lysophospholipid involved in diverse cellular processes such as cell proliferation, chemotaxis, platelet aggregation, wound healing, angiogenesis, tumor invasion, and smooth muscle contraction. LPA binds to several G-coupled protein receptors to initiate its biological functions. In cancer, LPA primarily promotes cell ...
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APPLY - Model TB-500 cas 77591-33-4 - Naturally Occuring, Potent Regulator

APPLY - Model TB-500 cas 77591-33-4 - Naturally Occuring, Potent Regulator

Manufactured by:Aike Import and Export Co.,Ltd   based in
Sequesters G-actin monomers in a 1:1 ratio (Kd = 0.7 - 1.0 μM) and allows rapid filament polymerization in the presence of profilin. Implicated in wound healing, induction of MMPs, chemotaxis, angiogenesis, inflammatory processes and tumor ...
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Flow CAST - Kinase Inhibition Assays

Flow CAST - Kinase Inhibition Assays

Manufactured by:BUHLMANN Diagnostics Corp    based inAmherst, NEW HAMPSHIRE (USA)
Flow CAST® Support in Drug Development: Inhibition of Basophil Activation is a Surrogate Biomarker for the Activity of Kinase ...
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Olinvacimab - Model TTAC-0001 - Anti-Angiogenic Antibody

Olinvacimab - Model TTAC-0001 - Anti-Angiogenic Antibody

Manufactured by:PharmAbcine Inc.   based inYuseong-gu, SOUTH KOREA
Olinvacimab is an anti-angiogenic antibody that neutralizes the VEGF/VEGFR2 pathway, thus inhibiting tumor growth and ...
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Model FT573 - B7 Family of Immune

Model FT573 - B7 Family of Immune

Manufactured by:Fate Therapeutics, Inc.   based inSan Diego, CALIFORNIA (USA)
B7H3 belongs to the B7 family of immune checkpoint inhibitors and is expressed on a wide range of solid and hematologic malignancies. B7H3 is an important mediator of tumor angiogenesis and metastasis, and higher expression is associated with a poor prognosis for patients. We are developing FT573, an investigational, universal, off-the-shelf NK cell cancer ...
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Viola - Model DBT Compact Design - Highly Versatile Digital Mammographic System

Viola - Model DBT Compact Design - Highly Versatile Digital Mammographic System

Manufactured by:General Medical Merate S.p.A. (GMM)   based inSeriate, ITALY
Highly versatile digital mammographic system with the latest FFDM and DBT technology, suitable for both screening and diagnostic mammography. Viola DBT Compact Design offers a wide range of functions, such as conventional 2D mammography, DBT (with synthetic image G-View), stereotactic or tomo-guided biopsies with close to 360° approach and Dual Energy (CESM). Thanks to the single-column stand ...
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Giotto - Model Class (30000 Series) - Advanced and Innovative Breast Tomosynthesis System

Giotto - Model Class (30000 Series) - Advanced and Innovative Breast Tomosynthesis System

Manufactured by:IMS Giotto S.p.A   based inSasso Marconi, ITALY
Advanced and innovative breast tomosynthesis system including the integrated capability to generate full-field digital mammography (FFDM) images. It offers a wide range of functions, such as FFDM, DBT (with optional synthetic image G-View), Dual Energy (CESM) and image-guided biopsy. Featuring a unique and ergonomic design to ensure patient comfort and easiness for the operator: the gantry is ...
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Giotto - Model Class S (40000 Series) - Digital Breast Tomosynthesis Device

Giotto - Model Class S (40000 Series) - Digital Breast Tomosynthesis Device

Manufactured by:IMS Giotto S.p.A   based inSasso Marconi, ITALY
Highly versatile digital mammographic system with the latest FFDM and DBT technology, suitable for both screening and diagnostic mammography. GIOTTO CLASS S offers a wide range of functions, such as conventional 2D mammography, DBT (with synthetic image G-View), stereotactic or tomo-guided biopsies with close to 360° approach and Dual Energy (CESM). Thanks to the single-column stand the ...
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Model L1CAM - Cell Surface Protein

Model L1CAM - Cell Surface Protein

Manufactured by:Elthera AG   based inSchlieren, SWITZERLAND
L1 cell adhesion molecule (L1CAM) is a cell surface protein which is aberrantly expressed in many different tumor types including pancreatic, ovarian, breast, lung, and colorectal cancer. L1CAM expression increases the malignancy of these tumors by promoting cellular proliferation, metastatic spread, tumor angiogenesis, ...
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Model ES104 - Bispecific Antibody

Model ES104 - Bispecific Antibody

Manufactured by:Elpiscience   based inShanghai, CHINA
ES104 is a bispecific antibody that simultaneously blocks Delta-like ligand 4/Notch (DLL4) and vascular endothelial growth factor A (VEGF-A) signaling pathways, which are critical to angiogenesis and tumor vascularization. VEGF also plays an important role in creating an immune suppressive TME. Pre-clinical and early clinical data of ES104 show that blocking both ...
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Viola - Model DBT - Advanced and Innovative Breast Tomosynthesis System

Viola - Model DBT - Advanced and Innovative Breast Tomosynthesis System

Manufactured by:General Medical Merate S.p.A. (GMM)   based inSeriate, ITALY
Advanced and innovative breast tomosynthesis system including the integrated capability to generate full-field digital mammography (FFDM) images. It features a unique and ergonomic design which ensures patient comfort and easiness for the operator: the gantry is able to reach different positions, including the horizontal one for interventional procedures. A high-precision tomo-guided biopsy kit ...
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MedChemExpress - Model Tivozanib - 475108-18-0

MedChemExpress - Model Tivozanib - 475108-18-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tivozanib (AV-951; KRN951) is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2 3, with IC50s of 30, 6.5 and 15 nM, respectively. Tivozanib exhibits antitumor ...
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Ceturegel - Model 40185ES - Basement Membrane Matrix

Ceturegel - Model 40185ES - Basement Membrane Matrix

Manufactured by:Yeasen Biotechnology (Shanghai) Co.,Ltd.   based inShanghai, CHINA
Ceturegel matrix, a kind of basement membrane matrix, is a soluble basement membrane preparation extracted from EHS mouse tumors rich in extracellular matrix proteins. It also contains growth factors such as TGF-beta, EGF, IGF, FGF and other related factors. Ceturegel™ Matrix GFR, LDEV-Free is a low growth factor matrigel obtained after special treatment, which can effectively ensure the ...
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Ceturegel - Model 40183ES - Basement Membrane Matrix

Ceturegel - Model 40183ES - Basement Membrane Matrix

Manufactured by:Yeasen Biotechnology (Shanghai) Co.,Ltd.   based inShanghai, CHINA
Ceturegel Matrix is a soluble basement membrane preparation extracted from EHS mouse tumors rich in extracellular matrix proteins. Its main components are laminin, type IV collagen, heparan sulfate proteoglycan (HSPG), nestin as well as growth factors such as TGF-beta, EGF, IGF, FGF, tissue plasminogen activator, and other growth factors contained in EHS tumors. Yeasen provides diverse kinds of ...
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MedChemExpress - Model Vandetanib - 443913-73-3

MedChemExpress - Model Vandetanib - 443913-73-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 ...
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MedChemExpress - Model Valproic acid sodium - 1069-66-5

MedChemExpress - Model Valproic acid sodium - 1069-66-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Valproic acid (Sodium Valproate) sodium is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic ...
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MedChemExpress - Model Isosorbide mononitrate - 16051-77-7

MedChemExpress - Model Isosorbide mononitrate - 16051-77-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Isosorbide mononitrate (Isosorbide-5-mononitrate) is an orally active nitric acid compound used for angina pectoris by dilating blood vessels and lowering blood pressure. Isosorbide mononitrate increases the viability and proliferation of HUVECs by decreasing Apoptosis and elevated the expressions of vedf, kdrl, pdgfr in zebrafish embryos. Isosorbide mononitrate is promising for research of heart ...
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MedChemExpress - Model Roxithromycin - 80214-83-1

MedChemExpress - Model Roxithromycin - 80214-83-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Roxithromycin (RU-28965) is an orally active semi-synthethic macrolide antibiotic. Roxithromycin inhibits protein biosynthesis in the elongation step by binding to 50S bacterial ribosome. Roxithromycin has antimicrobial, antiproliferative, anti-inflammatory, tumour vasculature inhibiting and lung injury ameliorating ...
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MedChemExpress - Model EOC317 - 939805-30-8

MedChemExpress - Model EOC317 - 939805-30-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
EOC317 (ACTB-1003) is an oral kinase inhibitor with IC50s of 6, 2 and 4 nM for FGFR1, VEGFR2 and ...
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MedChemExpress - Model Tivozanib hydrate - 682745-40-0

MedChemExpress - Model Tivozanib hydrate - 682745-40-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tivozanib hydrate (AV-951 hydrate; KRN951 hydrate) is the hydrate form of Tivozanib (HY-10977). Tivozanib hydrate is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2 3, with IC50s of 30, 6.5 and 15 nM, respectively. Tivozanib hydrate exhibits antitumor ...
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