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Cardiomyopathy Equipment & Supplies

23 equipment items found

iMatrix-221 - Model 5346 - Recombinant Laminin, 0.35 mg

iMatrix-221 - Model 5346 - Recombinant Laminin, 0.35 mg

Manufactured by:Advanced BioMatrix, Inc.   based inCarlsbad, CALIFORNIA (USA)
Laminin-221 is found predominantly in the basal lamina of striated muscle tissues. Expression deficiencies are implicated in muscular dystrophy and cardiomyopathies. iMatrix-221 is unique in that no pre-coating steps are necessary. This kit comes with 2 vials for a total of 0.35 mg of ...
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Model Acoramidis - TTR Stabilizer for ATTR-CM

Model Acoramidis - TTR Stabilizer for ATTR-CM

Manufactured by:BridgeBio Pharma, Inc.   based inPalo Alto, CALIFORNIA (USA)
variant of the TTR gene (T119M) that is considered a “rescue mutation” because it has been shown to prevent or minimize ATTR in individuals carrying pathogenic, or disease-causing, mutations in the TTR gene. Results from the ongoing Phase 3 study investigating acoramidis for symptomatic transthyretin amyloid cardiomyopathy (ATTR-CM), which includes mortality and ...
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Calcium Transients

Calcium Transients

Manufactured by:Ncardia Services B.V.   based inLeiden, NETHERLANDS
Disturbances in calcium signaling are associated with many neurodegenerative diseases and cardiomyopathies. Fluorescence-based assays with iPSC-derived cardiac and neuronal models can be used to monitor short and long-term drug-induced changes on calcium transients. Our scientists develop the most optimal calcium transient assay for each project and can scale it up for ...
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Celixir Heartcel - Immunomodulatory Progenitor Cells

Celixir Heartcel - Immunomodulatory Progenitor Cells

Manufactured by:Celixir plc   based inStratford-upon-Avon, UNITED KINGDOM
PHASE 2 : Our first investigational cardiac regenerative medicine consists of iMP cells. iMP cells are designed to treat patients with ischaemic heart disease – ischaemic cardiomyopathy – undergoing coronary artery bypass graft (CABG). They are injected around cardiac scar tissue via a single application during bypass ...
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Mediagnost - Coxsackievirus B3 Antibody

Mediagnost - Coxsackievirus B3 Antibody

Manufactured by:Mediagnost Gesellschaft für Forschung und Herstellung von Diagnostika GmbH    based inReutlingen, GERMANY
With the introduction of the in situ hybridization technique and polymerase chain reaction CVB3 RNA was not only detected in endomyocardial biopsies of patients with acute and chronic myocarditis but also in those suffering from dilated cardiomyopathy (Proc Natl Acad Sci U S A. 1987;84(17):6272-6; New Engl J Med 2000; 343, ...
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Cardiovascular NGS Panel

Cardiovascular NGS Panel

by:Tesis Biosciences   based inScottsdale, ARIZONA (USA)
The Cardiovascular NGS panel helps determine the risk of inherited heart disease, coronary artery disease including arrhythmias, congenital heart disease, cardiomyopathy, and high blood cholesterol. More than one in 200 patients have an inherited form of cardiovascular disease, with most people not knowing of their condition. These inherited heart diseases are conditions that are ...
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Danon Disease (DD)

Danon Disease (DD)

Manufactured by:Rocket Pharmaceuticals, Inc.   based inCranbury, NEW JERSEY (USA)
Danon Disease (DD) is a rare genetic disorder that is characterized by severe and primarily hypertrophic cardiomyopathy. Skeletal muscle weakness and mild cognitive impairment are also common. The causative mutation has been identified in the gene encoding for lysosome-associated membrane protein (LAMP2), and in particular the LAMP2B version of the gene which is primarily ...
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MedChemExpress - Model Ifetroban sodium - 156715-37-6

MedChemExpress - Model Ifetroban sodium - 156715-37-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ifetroban sodium shows antiplatelet activity, and inhibits tumor cell migration without affecting cell proliferation. Ifetroban sodium can be used for myocardial ischemia, hypertension, stroke, thrombosis, cardiomyopathy ...
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MedChemExpress - Model Sacubitril/Valsartan - 936623-90-4

MedChemExpress - Model Sacubitril/Valsartan - 936623-90-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure[1][2][3]. Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and ...
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JDB - Drug Candidate for Heart Disease

JDB - Drug Candidate for Heart Disease

Manufactured by:JD Bioscience Inc. (JDB)   based inBuk-gu, SOUTH KOREA
JDB is developing a novel drug candidate for heart disease that can rescue heart function at a cellular level, and can eventually help improving heart ...
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USRM - Adipo Cell

USRM - Adipo Cell

Manufactured by:U.S. Stem Cell, Inc. (USRM)   based inSunrise, FLORIDA (USA)
Adipose (fat) tissue is readily available and has been shown to be rich in microvascular, myogenic and angiogenic cells. In collaboration with the Regenerative Medicine Institute in Tijuana, Mexico, congestive heart failure patients are being treated in a Phase I/II trial at Hospital Angeles Tijuana. These patients have demonstrated on average an absolute improvement of 13 percentage points in ...
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Intellia - In Vivo Therapies

Intellia - In Vivo Therapies

by:Intellia Therapeutics, Inc.   based inCambridge, MASSACHUSETTS (USA)
The first patient was dosed with our investigational genome editing treatment for transthyretin (ATTR) amyloidosis in November 2020. Our modular approach enables us to optimize the power and versatility of the CRISPR/Cas9 technology and, importantly, allows us to rapidly develop therapeutics for numerous diseases that currently have limited treatment ...
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Kephera - Rapid Testing Tools for Chagas Disease

Kephera - Rapid Testing Tools for Chagas Disease

by:Kephera Diagnostics, LLC   based inFramingham, MASSACHUSETTS (USA)
With support from a National Institutes of Health grant, Kephera is developing a new point-of-care test for Chagas disease. Kephera scientists have identified and are purifying parasite components which promise to yield a highly sensitive and specific test. Together with our academic collaborators in the U.S. and Latin America, we are evaluating the performance of the test as it is developed in ...
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Fukuda Denshi Compatible Direct-Connect ECG Cable

Fukuda Denshi Compatible Direct-Connect ECG Cable

Manufactured by:Shenzhen Pray-Med Technology Co.,Ltd   based inShenzhen, CHINA
Category: ECG, Certifications: CE, ISO10993-1, 5, 10:2003E, TUV, RoHS Compliant, Connector Distal: 15-pin Fukuda Denshi Connector, Connector Proximal: Snap, Latex-free: Yes, Lead Cable Color: Gray, Lead Cable Diameter: 4 mm, Lead Cable Length Limb: 3 ft, Lead Cable Length V: 3 ft, Lead Cable Material: TPU Jacket, Lead Number: 5, Packaging Type: Bag, Packaging Unit: 1, Patient Size: ...
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Model cvi42 - Cardiovascular MRI

Model cvi42 - Cardiovascular MRI

Manufactured by:Circle Cardiovascular Imaging Inc.   based inCalgary, ALBERTA (CANADA)
cvi42 for Cardiac MRI has the most clinically cleared tools for diagnosis, and the most accurate tools to quantify and qualify for research purposes. ...
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MedChemExpress - Model Levosimendan - 141505-33-1

MedChemExpress - Model Levosimendan - 141505-33-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Levosimendan (Simsndan; OR-1259) is a calcium sensitiser used in the management of acutely decompensated congestive heart ...
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MedChemExpress - Model Megestrol acetate - 595-33-5

MedChemExpress - Model Megestrol acetate - 595-33-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Megestrol acetate is a synthetic and orally active progesteronal agent. Megestrol acetate is effective as an appetite stimulant for wasting syndromes such as cachexia. Megestrol acetate decreases nuclear and cytosol androgen receptors human BPH tissue. Megestrol acetate has the potential for HIV study and downregulates autophagic catabolic ...
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MedChemExpress - Model Lentinan - 37339-90-5

MedChemExpress - Model Lentinan - 37339-90-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Lentinan is an orally active biocompatible multifunctional polysaccharide with biological activities such as anti-inflammatory, antioxidant, immune regulation, anti-tumor, hypoglycemic, and ...
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Model Tempo-iCardio - Human iPSC-derived Cardiomyocytes

Model Tempo-iCardio - Human iPSC-derived Cardiomyocytes

Manufactured by:Tempo Bioscience, Inc   based inSan Francisco, CALIFORNIA (USA)
Cardiomyocytes are cardiac muscle cells. They are terminally differentiated and facilitate contractile forces (“beatings”) of the heart. Grown in vitro as a monolayer sheath, cardiomyocytes are connected by gap junction proteins that help synchronize contraction-relaxation cycles of the cardiomyocytes. Cardiomyocytes may be used in various in vitro or in vivo studies; ...
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MedChemExpress - Model Teneligliptin - 760937-92-6

MedChemExpress - Model Teneligliptin - 760937-92-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Teneligliptin (MP-513) hydrobromide hydrate is an orally active and selective dipeptidyl peptidase 4 (DPP-4) inhibitor (IC50s: 0.37 and 0.29 nM for the human and rat DPP-4, respectively). Teneligliptin hydrobromide hydrate improves blood glucose levels and can be used in researches related to type 2 diabetes ...
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