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Cell Based Assay Equipment & Supplies
31 equipment items found
by:Sword Diagnostics, Inc. based inCarmel, INDIANA (USA)
Sword scientists specialize in the development of qualitative or quantitative bioanalytical methods that measure cellular biomolecules active in a specific disease state. Cell-based assays are bioanalytical methods that measure the presence, amount, or activity of biomolecules in cells, cell fractions, nuclear ...
Manufactured by:Aurora Biomed Inc. based inVancouver, BRITISH COLUMBIA (CANADA)
Cell-based assays have always been a powerful tool in biological research laboratories. Recently, cell-based assays have become preferred over traditional biochemical assays by both the pharmaceutical and biotech industry because they provide a more in vivo-like environment for ...
Manufactured by:Cell Biolabs, Inc. based inSan Diego, CALIFORNIA (USA)
Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and ...
by:Sword Diagnostics, Inc. based inCarmel, INDIANA (USA)
Sword scientists will use our cell-based assay development expertise to develop a customized method to corroborate the binding specificity of your antibody-drug conjugate (ADC). Our understanding of the molecular basis of cellular growth, proliferation, and differentiation is continually evolving as the genes, proteins, and biochemical pathways ...
Manufactured by:ACROBiosystems based inNewark, DELAWARE (USA)
Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular ...
Manufactured by:ACROBiosystems based inNewark, DELAWARE (USA)
Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular ...
Manufactured by:Stem Pharm, Inc based inMadison, WISCONSIN (USA)
Stem Pharm’s technologies are based on functionalized multi-arm polyethylene glycol monomers that incorporate bioactive peptides to modulate adhesion and biomechanical properties. Our optimized substrates generate appropriate cellular environments that improve outcomes for cell expansion, differentiation, and in vitro ...
Manufactured by:Puracyp based inCarlsbad, CALIFORNIA (USA)
Puracyp’s nuclear receptor activation kits are all-inclusive cell-based assay systems. The kits incorporate mycoplasm-free, stably-transfected cells derived from hepatoma cell lines that have been treated with a cell-arrest agent to prevent further proliferation. Exposure to the ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth ...
Manufactured by:Endodiag based inParis, FRANCE
Endodiag has built a regulatory compliant biobank of more than 1000 human biological samples, including fixed biopsies, serum, plasma and peritoneal fluid samples, as well as endometriosis primary cell cultures and endometriosis derived cell lines. These samples are annotated with patients’ clinical data. EndoBiobank® together with the company’s ...
Manufactured by:OMass Therapeutics based inOxford, UNITED KINGDOM
OMass’ platform retains biological relevance at high resolution, delivering cell-system fidelity with cell-free ...
by:Resonant Sensors Incorporated (RSI) based inArlington, TEXAS (USA)
Guided-mode resonance (GMR) technology is a novel label-free optical approach that can measure a wide variety of molecular interactions in real-time using a standard microarray plate format. GMR signal(s) response is directly related to the binding density of the medium on the sensor surface. ...
Manufactured by:LI-COR Biotech, LLC based inLincoln, NEBRASKA (USA)
The Odyssey DLx Imaging System is a 2-channel near-infrared (NIR) fluorescent imager capable of producing high-quality Western blots, multi-well plate assays, tissue section images, and more. As an effective, high-throughput imager, the Odyssey DLx Imager takes exceptional, unsaturated images in a single acquisition without sacrificing image fidelity. Identical optical settings are used for every ...
Manufactured by:Shifa Biomedical Corporation based inMalvern, PENNSYLVANIA (USA)
LDLR is a cell-surface receptor that binds LDL-C and carries it into cells to the endosome for degradation and thus reduces the plasma level of LDL-C (Figure 1). However, PCSK9 controls the degradation of the LDLR in the liver (Figure 1) and thereby contributes to cholesterol ...
by:Orion Biotechnology Canada, Ltd. based inOttawa, SWITZERLAND
G Protein-Coupled Receptors (GPCRs) are involved in a wide range of physiological and pathological processes and represent a large class of drug targets accounting for >30% of all drugs on the market. These drugs, however, only cover 15% of the entire GPCR family, and many valuable receptors remain undrugged. In particular, GPCRs whose natural ligands are large peptides or small proteins are ...
Manufactured by:Orbit Discovery based inOxford, UNITED KINGDOM
Orbit presents DNA and peptide on the surface of a microbead. This allows for unbiased libraries and a tunable multivalent display that gives access to huge chemical diversity. Our display technology can deal with unnatural amino acids and complex peptide constraints. It can display a peptide via complex scaffolds and makes whole cell screening and functional hits possible. ...
by:Sibylla Biotech S.p.A. based inVerona, ITALY
In Silico: Identifying small molecules able to revolutionize drug discovery. The PPI-FIT technology allows the exploration of unique pharmacological targets represented by protein folding intermediates. This places Sibylla Biotech in the exclusive position of identifying hit/lead compounds with a mechanism of action never explored so far. In this direction, we have developed an ad-hoc virtual ...
by:AdAlta Limited based inBundoora, AUSTRALIA
An i-body is a human protein that belongs to the class of next generation antibodies. The i-body is built on the scaffold of a human protein and engineered with two loops that mimic the shape of shark antibodies. These loops are responsible for binding or interacting with a particular target (in circulation or on a cell) that is causing disease. i-bodies are identified and developed using our ...
Manufactured by:InterTech Development Company based inSkokie, ILLINOIS (USA)
Proven InterTech Microscale Technology measures leaks down to the equivalent of a 0.5 micron defect diameter. A careful review of application requirements including the Maximum Allowable Leakage Limit (MALL) will dictate the test method used. Testing is consistent with ASTM requirements (F-3287-17, F-2338-09). Proprietary technology is available for testing with minimal headspace volumes. ...
Manufactured by:Sphere Fluidics Limited based inCambridge, UNITED ARAB EMIRATES
The CellJet bioprinter by Cellular Life Sciences is a flexible, non-contact system designed for printing cells and hydrogels in any 2D and 3D configuration onto any microwell plate, culture dish, or custom surface. Featuring Digilab® ‘s proprietary synQUAD liquid dispensing technology, CellJet enables both on-the-fly and drop-by-drop cell printing, while preserving the viability of even ...