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  • Liposomes - Hollow Nanospheres for Gene Therapy
  • Liposomes - Hollow Nanospheres for Cancer Therapy
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Cholesterol Reducing Equipment & Supplies

19 equipment items found

Vaxxinit - Model PCSK9 - Lower LDL Cholesterol

Vaxxinit - Model PCSK9 - Lower LDL Cholesterol

by:Vaxxinit   based inDallas, TEXAS (USA)
Targets PCSK9 to lower LDL cholesterol and reduce the risk of cardiac ...
CONTACT SUPPLIER

Firsky - Model CAS 83-44-3 - Deoxycholic Acid

Firsky - Model CAS 83-44-3 - Deoxycholic Acid

Manufactured by:Firsky International Trade (Wuhan) Co., Ltd.   based inWuhan, CHINA
Deoxycholic acid is a bile acid that is naturally produced in the liver and stored in the gallbladder. It plays an important role in the digestion and absorption of dietary fats in the small intestine. Deoxycholic acid is also available as a medication and is commonly used for cosmetic ...
CONTACT SUPPLIER

Cardiovascular Disease/Hypertension

Cardiovascular Disease/Hypertension

Manufactured by:Realize Therapeutics Corp.   based inLake Bluff, ILLINOIS (USA)
Heart disease is one of the most common causes of death worldwide. Intestinal flora affect blood sugar and heart health by reducing cholesterol levels, blood pressure and inflammation. Realize products based on microbiome restoration and modulation are being developed to treat cardiovascular and hypertension ...
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Sumitomo - Model DSP-0390 - Emopamil-Binding Protein (EBP) Inhibitor

Sumitomo - Model DSP-0390 - Emopamil-Binding Protein (EBP) Inhibitor

by:Sumitomo Pharma Oncology, Inc.   based inCambridge, MASSACHUSETTS (USA)
DSP-0390 is an emopamil-binding protein (EBP) inhibitor. EBP is an endoplasmic reticulum membrane protein involved in cholesterol biosynthesis.47 When functional, EBP mediates de novo cholesterol synthesis for cell membrane structure and signaling, enabling aberrant growth of tumors.47-50 Inhibition of EBP causes an accumulation of its substrates zymostenol and zymosterol, which contributes to ...
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MedChemExpress - Model Fluvastatin - 93957-54-1

MedChemExpress - Model Fluvastatin - 93957-54-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant ...
CONTACT SUPPLIER

MedChemExpress - Model AACOCF3 - 149301-79-1

MedChemExpress - Model AACOCF3 - 149301-79-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeant trifluoromethyl ketone analog of arachidonic acid. AACOCF3 is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). AACOCF3 blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. AACOCF3 inhibits glucose-induced insulin secretion from ...
CONTACT SUPPLIER

MedChemExpress - Model YM-53601 - 182959-33-7

MedChemExpress - Model YM-53601 - 182959-33-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
YM-53601, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo[1]. YM-53601 inhibits squalene synthase derived from human hepatoma cells with an IC50 of 79 nM. Lipid-lowering agent[2]. YM-53601 is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and abrogates HCV ...
CONTACT SUPPLIER

MedChemExpress - Model Fluvastatin sodium - 93957-55-2

MedChemExpress - Model Fluvastatin sodium - 93957-55-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin sodium protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant ...
CONTACT SUPPLIER

MedChemExpress - Model Elsibucol - 216167-95-2

MedChemExpress - Model Elsibucol - 216167-95-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Elsibucol is a metabolically stable propanol derivative with antioxidant, anti-inflammatory and anti-proliferative properties. Elsibucol lowers blood cholesterol levels and reduces oxidative stress and inflammatory responses in injured arteries, thereby inhibiting atherosclerosis and protecting endothelial healing after arterial ...
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MedChemExpress - Model Pantethine - 16816-67-4

MedChemExpress - Model Pantethine - 16816-67-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related ...
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MedChemExpress - Model Ro 48-8071 - 161582-11-2

MedChemExpress - Model Ro 48-8071 - 161582-11-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ro 48-8071 is an inhibitor of OSC (Oxidosqualene cyclase) with IC50 of appr 6.5 ...
CONTACT SUPPLIER

Nanovex - Model Liposomes - Hollow Nanospheres

Nanovex - Model Liposomes - Hollow Nanospheres

Manufactured by:Nanovex Biotechnologies   based inLlanera, SPAIN
Liposomes are hollow nanospheres made of a double lipidic layer that enclose an aqueous core. They are similar to micelles besides the size and the number of lipidic ...
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MedChemExpress - Model SC-435 - 289037-67-8

MedChemExpress - Model SC-435 - 289037-67-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
SC-435 is an orally effective apical sodium codependent bile acid transporter (ASBT) inhibitor. SC-435 effectively removes neurotoxic bile acids and ammonia from the blood by inhibiting intestinal ASBT, thereby alleviating liver and brain damage caused by liver failure. SC-435 can alter hepatic cholesterol metabolism and lower plasma low-density lipoprotein-cholesterol concentrations[1] [2] ...
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MedChemExpress - Model Alirocumab - 1245916-14-6

MedChemExpress - Model Alirocumab - 1245916-14-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Alirocumab is an anti-PCSK9 human monoclonal antibody. Alirocumab inhibits PCSK9. Alirocumab reduces NLRP3 inflammasome, regulates Nrf2/HO-1, HMGB1/NF-κB and Fractalkine/CX3CR1. Alirocumab increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. Alirocumab improves atherosclerosis and ...
CONTACT SUPPLIER

MedChemExpress - Model Ro 48-8071 fumarate - 189197-69-1

MedChemExpress - Model Ro 48-8071 fumarate - 189197-69-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ro 48-8071 fumarate is an inhibitor of OSC (Oxidosqualene cyclase) with IC50 of appr 6.5 ...
CONTACT SUPPLIER

MedChemExpress - Model Enclomiphene citrate - 7599-79-3

MedChemExpress - Model Enclomiphene citrate - 7599-79-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Enclomiphene ((E)-Clomiphene) citrate is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene citrate can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 ...
CONTACT SUPPLIER

MedChemExpress - Model Enclomiphene hydrochloride - 14158-65-7

MedChemExpress - Model Enclomiphene hydrochloride - 14158-65-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Enclomiphene ((E)-Clomiphene) hydrochloride is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene hydrochloride can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 ...
CONTACT SUPPLIER

OptiBiotix - Human Microbiome Technology

OptiBiotix - Human Microbiome Technology

Manufactured by:OptiBiotix Health Plc.   based inHeslington, UNITED KINGDOM
The human digestive tract contains a complex and diverse ecosystem of trillions of microorganisms, mainly bacteria. Recent advances in molecular and analytical techniques have permitted identification of bacterial species and strains that inhabit the gastrointestinal tract, their metabolic activity, and interactions with the human host. These studies have provided greater insight into the role ...
CONTACT SUPPLIER

MedChemExpress - Model Alirocumab (anti-PCSK9) - 1245916-14-6

MedChemExpress - Model Alirocumab (anti-PCSK9) - 1245916-14-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Alirocumab (anti-PCSK9) is an anti-PCSK9 human monoclonal antibody. Alirocumab (anti-PCSK9) inhibits PCSK9. Alirocumab (anti-PCSK9) reduces NLRP3 inflammasome, regulates Nrf2/HO-1, HMGB1/NF-κB and Fractalkine/CX3CR1. Alirocumab (anti-PCSK9) increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. ...
CONTACT SUPPLIER
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