Collagen Induced Equipment & Supplies
54 equipment items found
by:Abivax based inParis, FRANCE
In addition to the clinical observations in UC patients, Abivax generated excellent phase 2a clinical results in RA, following the promising pre-clinical data from collagen-induced arthritis animal ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
L-161982 is a selective EP4 receptor antagonist. L-161982 completely blocks PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells. L-161982 alleviates collagen-induced arthritis in ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
GLPG0259 is a ATP-competitive inhibitor of MAPK-activated protein kinase 5 (MK5) with oral activity. GLPG0259 reduces inflammation and bone destruction in a mouse model of collagen-induced arthritis. GLPG0259 also inhibited the metastasis of prostate cancer (PCa) ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
UNC2881 shows additional inhibition against Axl and Tyro with IC50s of 360 nM and 250 nM, respectively. UNC2881 potently inhibits collagen-induced platelet aggregation, can be used for pathologic thrombosis ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
TMI-1 (WAY-171318) inhibits TNF converting enzyme (TACE) (IC50 of 8.4 nM), ADAM-TS-4, ADAM-17 and various MMPs with oral activity. TMI-1 significantly suppresses the secretion of TNF-α , alleviating collagen-induced arthritis in mice. TMI-1 inhibits cancer cell proliferation, induces apoptosis through a caspase-dependent pathway. TMI-1 also ...
Manufactured by:MBP – Medical Biomaterial Products GmbH based inNeustadt-Glewe, GERMANY
MB-Collagen is a collagen based dressing for wound care and traumatic, slowly healing wounds like Decubitus or leg ulcers (Ulcus cruris). The effectiveness of MB-Collagen is based on one hand on the chemotactic effects of the collagen matrix leading to a settlement of fibroblasts on the wound bed. On the other hand exogen collagen promotes binding of proteases. Both mechanisms are acting ...
Manufactured by:MBP – Medical Biomaterial Products GmbH based inNeustadt-Glewe, GERMANY
Surgicoll Plug is a fully resorbable sponge like cone formed collagen matrix for effective hemostasis. Collagen is well known for its outstanding properties as hemostatic agent documented in numerous clinical reports. The sponge like collagen matrix promotes reliable blood clotting due to two complementarily acting mechanisms. While the ...
Manufactured by:Lohmann & Rauscher GmbH & Co. KG (L&R) based inRengsdorf, GERMANY
The Suprasorb C Collagen Wound Dressing has a porous structure with highly pronounced capillary activity, allowing absorption of fluid. This physical property allows continuous absorption of exudate, debris (such as necrotic tissue, fibrin slough) and inflammatory proteases and cytokines. This promotes and accelerates formation of granulation tissue. Migration of fibroblasts is ...
Manufactured by:MBP – Medical Biomaterial Products GmbH based inNeustadt-Glewe, GERMANY
Surgicoll is a fully resorbable sponge like collagen matrix for effective hemostasis. Collagen is well known for its outstanding properties as hemostatic agent documented in numerous clinical reports. The sponge like collagen matrix promotes reliable blood clotting due to two complementarily acting mechanisms. While the collagen ...
Manufactured by:MBP – Medical Biomaterial Products GmbH based inNeustadt-Glewe, GERMANY
Surgicoll Cloud is a fully resorbable microfibrillar collagen matrix for effective hemostasis. Collagen is well known for its outstanding properties as hemostatic agent documented in numerous clinical reports. The sponge like collagen matrix promotes reliable blood clotting due to two complementarily acting mechanisms. While the ...
Manufactured by:Iskra Medical d.o.o. based inPodnart, SLOVENIA
A powerfull combination of ultrasound and RDT®technology leads to the unique vacuum cavitation treatment that entails highly effective and risk-free body contouring. The vacuum cavitation systems therefore provide non-invasive, painless,safe, and fast alternative to the liposuction procedures as well as effective cellulite reduction.Various body sites can be contoured with no anesthesia, no ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Betahistine dihydrochloride is an orally active histamine H1 receptor agonist and a H3 receptor antagonist[1]. Betahistine dihydrochloride is used for the study of rheumatoid arthritis ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Y-320 is a potent, orally active phenylpyrazoleanilide immunomodulator. Y-320 inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM. Y-320 enhances TP53, DMD, and COL17A1 PTC readthrough by G418 and increases cellular protein levels and protein synthesis. Y-320 concomitants use of with a low dose of Paclitaxel (HY-B0015) significantly sensitized multidrug ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Betahistine mesylate is an orally active histamine H1 receptor agonist and a H3 receptor antagonist[1]. Betahistine mesylate is used for the study of rheumatoid arthritis ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38α and p38β, respectively. Pamapimod has no activity against p38δ or p38γ isoforms. Pamapimod has the potential for rheumatoid arthritis and other autoimmune diseases ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
RVX-297 is a potent, orally active BET bromodomain inhibitor with selectivity for BD2. RVX-297 shows IC50s of 0.08, 0.05, and 0.02 μM for BRD2(BD2), BRD3(BD2), and BRD4(BD2), respectively. RVX-297 suppresses inflammatory gene expression in multiple immune cell types. RVX-297 is effective in acute inflammation and autoimmunity ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
PKRA83 (PKRA7) is a potent prokineticin (PK2) antagonist, which can compete for the binding of PK2 to its receptors PKR1 and PKR2. PKRA83 potently inhibits PK2 receptors, with IC50 values of 5.0 nM and 8.2 nM for PKR1 and PKR2, respectively. PKRA83 has anticancer, anti-arthritis and anti-angiogenic activities. PKRA83 can penetrate the blood-brain ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
WRG-28 is a selective, extracellularly acting DDR2 allosteric inhibitor, with an IC50 of 230 nM. WRG-28 inhibits tumor invasion, migration and tumor-supporting effects of cancer-associated fibroblasts (CAFs). WRG-28 inhibits metastatic breast tumor cell colonization in the lungs. WRG-28 also shows good activity of relieving rheumatoid arthritis in CAIA model of ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Betahistine is an orally active histamine H1 receptor agonist and a H3 receptor antagonist[1]. Betahistine is used for the study of rheumatoid arthritis ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Meseclazone (W2395;NSC297623) exhibits inhibitory potency of secondary phase ADP aggregation. Meseclazone possesses anti-inflammatory, analgesic and antipyretic ...