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Cytokine Secreting Equipment & Supplies
28 equipment items found
Manufactured by:Eutilex Co.,Ltd. based inSeoul, SOUTH KOREA
The epitopes recognized by HLA-DR are not shed or internalized, enabling stable binding to human lymphoma cells. MVR CAR-T can also be used in patients who relapse after CD19 CAR-T treatment. Reduction of cytokine secretion due to selective killing of tumor ...
Manufactured by:RoosterBio, Inc. based inFrederick, MARYLAND (USA)
Lots are released based on hMSC identity (cell surface marker expression), expansion, viability, sterility, and differentiation and provided QC Brief containing industry-leading functional characterization (immunomodulatory potential (IDO assay), angiogenic cytokine ...
Manufactured by:Creative BioMart based in, NEW YORK (USA)
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes ...
Manufactured by:RoosterBio, Inc. based inFrederick, MARYLAND (USA)
Accompanying QC brief contains industry-leading functional characterization including immunomodulatory potential (IDO assay) and angiogenic cytokine secretion, giving added confidence in quality, reproducibility, and ease of integration. ...
Manufactured by:Krishgen Biosystems based inMumbai, INDIA
Tumor necrosis factor alpha (TNF ±) is a multifunctional cytokine secreted primarily by macrophages, natural killer (NK) cells, and lymphocytes.The main function of TNF Alpha is to regulate the immune cells. It has the ability to induce a fever, speed up cell death, create inflammation etc. It stimulates the acute phase response on the liver, which can ...
Manufactured by:Obsidian Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
Our proprietary cytoDRiVE® platform leverages drug responsive domains (DRDs) to control protein function using an FDA-approved small ...
Manufactured by:RoosterBio, Inc. based inFrederick, MARYLAND (USA)
RoosterVial™-hBM-XF are Human Bone-Marrow Derived Mesenchymal Stem/Stromal Cells (hBM-MSCs) isolated from adult human iliac crest from a variety of normal, healthy donors and expanded to a population doubling level (PDL) of 6-10, post-mononuclear cell isolation. Available in both 1M or high-volume 10M cell per vial formats to meet your needs throughout product development. ...
Manufactured by:RoosterBio, Inc. based inFrederick, MARYLAND (USA)
RoosterVial™-hUC-XF are Human Umbilical Cord Derived Mesenchymal Stem/Stromal Cells (hUC-MSCs) isolated from the perivascular Wharton’s Jelly region of the human umbilical cord and expanded to a population doubling level (PDL) of 6-10, post-mononuclear cell isolation. Available in both 1M or high-volume 10M cell per vial formats to meet your needs throughout product development. ...
Manufactured by:ProImmune Ltd. based inOxford, UNITED KINGDOM
ProM2® MHC Class II Monomers, biotinylated enabling specialist assays for defined MHC Class II peptide target interactions. Best in class MHC Class II Monomers: ProM2® Class II MHC Monomers are pre-biotinylated and can be readily adapted either to detect and separate single-antigen specific T cells or implement specialist solid or solution phase immunoassays for measuring interactions of ...
Manufactured by:Fate Therapeutics, Inc. based inSan Diego, CALIFORNIA (USA)
NK cells express CD16, an activating receptor that binds to the Fc portion of IgG antibodies. Once activated through CD16, NK cells are able to destroy antibody-coated target cells and secrete cytokines, such as interferon gamma, to recruit and potentiate adaptive immune cells, including T cells. This mechanism of action, referred to as antibody-dependent ...
Manufactured by:Fate Therapeutics, Inc. based inSan Diego, CALIFORNIA (USA)
The oncology therapeutic landscape has been transformed with the use of checkpoint inhibitor therapy. Despite the clinical benefit conferred by approved checkpoint inhibitor therapy against a variety of tumor types, these therapies are not curative and, in most cases, patients either fail to respond or their disease progresses on these agents. Resistance to checkpoint inhibitor therapy has been ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
ABR-238901 is an orally active and potent S100A8/A9 blocker and inhibits S100A8/A9 interaction with its receptors RAGE (receptor for advanced glycation endproducts) and TLR4 (toll-like receptor 4). ABR-238901 has the potential for myocardial infarction (MI) ...
Manufactured by:ProImmune Ltd. based inOxford, UNITED KINGDOM
ProT2® MHC Class II Tetramers track antigen-specific CD4+ T cells with the most comprehensive class II tetramer catalog range now also available for H-2 IAb, IAd, ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Cetirizine dihydrochloride, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine dihydrochloride marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Crisaborole (AN-2728) is a potent inhibitor of PDE4 and cytokine release; inhibit PDE4 with an IC50 of 0.49 ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Lucatumumab (HCD122) is a fully human anti-CD40 antagonist monoclonal antibody, which blocks CD40/CD40L-mediated signaling. Lucatumumab efficiently mediates antibody-dependent cell-mediated cytotoxicity (ADCC) and clearance of tumor cells, can be used for refractory lymphomas, CLL and multiple myeloma ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Malabaricone C is an orally active and noncompetitive sphingomyelin synthase (SMS) inhibitor with IC50 values of 3 μM and 1.5 μM for SMS 1 and SMS 2, respectively. Malabaricone C reduces body weight gain, improves glucose tolerance, and decreases lipid accumulation in the liver, showing significant prevention of high fat diet-induced fatty liver in mice. Malabaricone C has anti-inflammatory ...
Manufactured by:Sepset Biosciences Inc. based inVictoria, BRITISH COLUMBIA (CANADA)
Sepset is developing a blood test for hospitals to identify septic patients in the emergency room (ER) and predict those who will have high risk for organ ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Zabedosertib (BAY 1834845) is a selective, orally active IRAK4 inhibitor with immunomodulatory potential, IC50 is 3.55 nM. IRAK4 is a protein kinase involved in signaling innate immune responses from Toll-like receptors[1]. Zabedosertib exhibits anti-inflammatory property against IL-β, LPS (HY-D1056) and Imiquimod (HY-B1080) induced ...